Mouse Anti-D. melanogaster Chmp2B Antibody (CBMOAB-13497FYA)
Cat: CBMOAB-13497FYA
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Fruit fly (Drosophila melanogaster) |
| Clone | MO13497FYA |
| Specificity | This antibody binds to fruit fly Chmp2B. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Endosome |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration. |
| Product Overview | Mouse Anti-D. melanogaster Chmp2B Antibody is a mouse antibody against Chmp2B. It can be used for Chmp2B detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Charged multivesicular body protein 2b; LD36173p; CHMP2B |
| UniProt ID | Q9VRJ5 |
| Protein Refseq | The length of the protein is 212 amino acids long. The sequence is show below: MFNNIFGKKPTVKEQQRENDRSLRKATRDIERERRKMEEEERKLELEIRRNAAAGNNDACRILAKQLVEIRKQKSRTYAAAGKIQSIGYQNKNMGANIALSEAMGTTAKTMGEMNKVMRPEAIGETVRQFQAANMKMEMTDEMINDTLDDMLNESGDEEESNAVVNKVLDEIGIEISGKMSSIPATGSSDFETSGKRTEKDIADQLAKLRSS. |
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For Research Use Only | Not For Clinical Use.
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