Mouse Anti-D. melanogaster Dif Antibody (CBMOAB-14835FYA)


Cat: CBMOAB-14835FYA
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Size:
Conjugate:
 Inquiry
  • Specifications
  • Application Information
  • Target

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFruit fly (Drosophila melanogaster)
CloneMO14835FYA
SpecificityThis antibody binds to fruit fly Dif.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionMediates an immune response in larvae (PubMed:8242747). DIF binds to the kappa-B consensus sequence 5''-GGRNNYYCC-3'', located in the enhancer region of the immunity gene CECA1 (PubMed:8242747). Involved in the melanization immune response to bacterial challenge, possibly by acting in a Toll signaling pathway that downregulates Spn27A in response to infection (PubMed:12456640). Part of a signaling pathway involving NF-kappa-B (rel) and Toll-related receptors, that functions in the apoptosis of unfit cells during cell competition (PubMed:25477468). May be part of a NF-kappa-B and Tollo signaling cascade that regulates development of the peripheral nervous system (PubMed:18000549). (From uniprot, under CC BY 4.0)
Product OverviewMouse Anti-D. melanogaster Dif Antibody is a mouse antibody against Dif. It can be used for Dif detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesDorsal-related immunity factor, isoform C; Dif
UniProt IDE1JHK2
Protein RefseqThe length of the protein is 987 amino acids long.
The sequence is show below: MFEEAFGDIQEIINASMELNGGATGGGSVAGAVGGGGAAHHILSQSTSLPVMPSHIPLHLQNQNMNQNLPEPSARSGPHLRIVEEPTSNIIRFRYKCEGRTAGSIPGMNSSSETGKTFPTIEVCNYDGPVIIVVSCVTSDEPFRQHPHWLVSKEEADACKSGIYQKKLPPEERRLVLQKVGIQCAKKLEMRDSLVERERRNIDPFNAKFDHKDQIDKINRYELRLCYQAFITVGNSKVPLDPIVSSPIYGKSSELTITRLCSCAATANGGDEIIMLCEKIAKDDIEVRFYETDKDGRETWFANAEFQPTDVFKQMAIAFKTPRYRNTEITQSVNVELKLVRPSDGATSAPLPFEYYPNPGTVTFARLQRKLKRRQELDVFQQILSLDSETTATKYSCPPMDLEEDNNTVSSDDQQSSGTLNEFEIAVKKMQMRQRGESHEMDGGTVTEYTDNDNEPDMEIELEVPQLLPQLADDCTQTSTPMEEILQHPQLQSRPLSNVETITEWMKSSEFERTDSLTVENGDTQSLSNSTAQTAFTNVSSLTANTTITNQLDEEAHGLLANGSRRDTLENPAVKELPENEKEPEMVSASAQASMDLDENFDETATYTSLQIAFNNPIDIGLPKESKQAAPIYPPTNPFGQLDDDELVVLTNPPAPRIKVNAAQTPATPPASPPLPLPPRTPSPVSDQRLPPLPPKPQRNSQDLSAVSDSISVSRSRNGSLSSNRTTPSPIIIMRTPDQSPTKRQPTPSASPKKRQGFFSRFFSRRRSKTDDEESLTPGGSPNKQLPGGSKATTPTGSREPSVAHFSLGDPNRSSTRSMQPLGKSEGRNGKPVGRSSSSVSGKRPAHLDADVIHIPLKGGDSENSLLRPESYSNASTLSYGRPLDRKTLSTLQLADIPISDGNMELIAIADRQSIKNLCEGAYGVVLDPSVDLSEAEHFALYTSKSPEPPFGGECGEGGAATGGVDTTDFLSADEIARRLAEANGLE.
For Research Use Only | Not For Clinical Use.
Online Inquiry