AibGenesis™ Mouse Anti-Dmtn Antibody (CBMOAB-14977FYA)


Cat: CBMOAB-14977FYA

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Lot Number

  • Product List
  • Specifications
  • Application Information
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Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-14977FYA Monoclonal Fruit fly (Drosophila melanogaster), Frog (Xenopus laevis), Rhesus (Macaca mulatta), Zebrafish (Danio rerio) WB, ELISA MO14977FYA 100 µg
CBMOAB-40918FYA Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO40918FYA 100 µg
CBMOAB-73741FYA Monoclonal Zebrafish (Danio rerio) WB, ELISA MO73741FYA 100 µg
MO-AB-02476W Monoclonal Fruit fly (Drosophila melanogaster) WB, ELISA MO02476W 100 µg
MO-AB-03019H Monoclonal Frog (Xenopus laevis) WB, ELISA MO03019C 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFruit fly (Drosophila melanogaster), Frog (Xenopus laevis), Rhesus (Macaca mulatta), Zebrafish (Danio rerio)
CloneMO14977FYA
SpecificityThis antibody binds to fruit fly Dmtn.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationPlasma Membrane; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene is an actin binding and bundling protein that plays a structural role in erythrocytes, by stabilizing and attaching the spectrin/actin cytoskeleton to the erythrocyte membrane in a phosphorylation-dependent manner. This protein contains a core domain in the N-terminus, and a headpiece domain in the C-terminus that binds F-actin. When purified from erythrocytes, this protein exists as a trimer composed of two 48 kDa polypeptides and a 52 kDa polypeptide. The different subunits arise from alternative splicing in the 3' coding region, where the headpiece domain is located. Disruption of this gene has been correlated with the autosomal dominant Marie Unna hereditary hypotrichosis disease, while loss of heterozygosity of this gene is thought to play a role in prostate cancer progression. Alternative splicing results in multiple transcript variants encoding different isoforms. (From NCBI)
Product OverviewMouse Anti-D. melanogaster Dmtn Antibody is a mouse antibody against Dmtn. It can be used for Dmtn detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesCG1021, isoform H; Dmtn
UniProt IDE1JJ71
Protein RefseqThe length of the protein is 679 amino acids long.
The sequence is show below: MDTTPNAAPNPNQNRDFVTLKPLRPSRGSSSNLRASRSPSASRSTEQMSRERASEAAAATQTAAATAGGATAHSAGGTAGGSAAATTTAGGATSGSGTASANTNSNSSASSSTVAAAQAAVYSGGNTVTGSLGSAGVVARGFRSHSPTHRRRSRERQRRTHGSDQGGLLAYSGLVGVNDMTDFLGPQQGGGGGGGGGGGGGGGGGSAGTGSGLEDSRLSGNEDYYSSFVSDEFDSSKKVHRRCHERSSSVQAIDRLNTKIQCTKESIRQEQTARDDNVNEYLKLAASADKQQLQRIKAVFEKKNQKSAHNISQLQKKLDNYTKRAKDLQNHQFQTKSQHRQPREVLRDVGQGLRNVGGNIRDGITGFSGSVMSKPREFAHLIKNKFGSADNINQMSEAELQGMQSANADVLGSERLQQVPGAGTSTGSGGGGQNNNTGGAGSGTGKFNSDNGSECSSVTSESIPGGSGKSQSGASQYHIVLKTLLTELAERKAENEKLKERIERLETGQKEFNNLTATLESERYRAEGLEEQINDLTELHQNEIENLKQTIADMEEKVQYQSDERLRDVNEVLENCQTRISKMEHMSQQQYVTVEGIDNSNARALVVKLINVVLTILQVVLLLVATAAGIIMPFLKTRVRVLTTFLSICFVIFVIRQWPDVQDIGSGLVRHLKQSLVVK.
For Research Use Only | Not For Clinical Use.
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