Mouse Anti-D. melanogaster Gclc Antibody (CBMOAB-17302FYA)
Cat: CBMOAB-17302FYA
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Fruit fly (Drosophila melanogaster) |
| Clone | MO17302FYA |
| Specificity | This antibody binds to fruit fly Gclc. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Nucleus; Other locations |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction. |
| Product Overview | Mouse Anti-D. melanogaster Gclc Antibody is a mouse antibody against Gclc. It can be used for Gclc detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Glutamate--cysteine ligase; EC 6.3.2.2; Gamma-ECS; GCS; Gamma-glutamylcysteine synthetase; Gclc; GCSh |
| UniProt ID | Q9W3K5 |
| Protein Refseq | The length of the protein is 717 amino acids long. The sequence is show below: MGLLSEGSPLSWEETKALADHVREHGVNQFINLYHRLKDRQGDILKWGDEVEYIIVKFDDEQKVARVALRAQDLLAQLNEKELADPNGVKSLWRPEYGAYMIEGTPGKPFGGLMAHFNLVEANMRYRREEVTELLAKDECVMSITNFPRLGAPNFTYPLAQPRPEDPLSSARSLYFPDEAIFPGHPRFKTLTRNIRKRRGEKVSIKLKVFKDTKTKLPVEGAPPGEPDVVLLDAMGFGMGCCCLQLTFQACNITEARRLYDQLAPLCPIMLALTAASPIYRGYLTESDCRWNVISSSVDCRTEEERGLAPLDQQKFRIAKSRYDSIDSYLSPEGAKYNDVPLTYDEKVYQRLVEGGIDHLLAQHVAHLFIRDTVSLFSEKVHQNDNEDTDHFENIQSTNWQTMRFKPPPPNSSIGWRVEFRPCEAQISDFENAAIVCFVVLLTRVILSYQLNFLTPISKVDENMQTAQKRDACRKEKFWFRKSSKTTEQRAAKAQAQAQAQAKAQAQTNGKATLNGNGLANGNGNGSENSDQEEQQPLTNGSAKMNGHGSGTTNGTNGSSNGSSNGTDSDHTDTDDEENELFQLLSINEIFNGKPNVFPGLVPLIRSYLQSMEVDTDTHCTIEQYLRFIQKRAAGELITTATWMREQVLSHPDYKQDSVVSERINYDLLKRIQGIQEGKQVEPALLGQDYHSKTKTKDFIPPALQKQLAKNGCCEEK. |
See other products for " GCLC "
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| MO-AB-12937R | Mouse Anti-Cattle GCLC Antibody (MO-AB-12937R) |
| MO-AB-03846H | Mouse Anti-Frog gclc Antibody (MO-AB-03846H) |
| MO-AB-55913W | Mouse Anti-Marmoset GCLC Antibody (MO-AB-55913W) |
| CBMOAB-77692FYA | Mouse Anti-Zebrafish gclc Antibody (CBMOAB-77692FYA) |
For Research Use Only | Not For Clinical Use.
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