Mouse Anti-Gclc Antibody (CBMOAB-17302FYA)

Cat: CBMOAB-17302FYA

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Lot Number

Product List
Specifications
Application Information
Target

Sub Cat	Clonality	Species Reactivity	Application	Clone	Conjugate	Size
CBMOAB-17302FYA	Monoclonal	Fruit fly (Drosophila melanogaster), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Marmoset, Zebrafish (Danio rerio)	WB, ELISA	MO17302FYA		100 µg	Inquiry
Protein Refseq: The length of the protein is 717 amino acids long. The sequence is show below: MGLLSEGSPLSWEETKALADHVREHGVNQFINLYHRLKDRQGDILKWGDEVEYIIVKFDDEQKVARVALRAQDLLAQLNEKELADPNGVKSLWRPEYGAYMIEGTPGKPFGGLMAHFNLVEANMRYRREEVTELLAKDECVMSITNFPRLGAPNFTYPLAQPRPEDPLSSARSLYFPDEAIFPGHPRFKTLTRNIRKRRGEKVSIKLKVFKDTKTKLPVEGAPPGEPDVVLLDAMGFGMGCCCLQLTFQACNITEARRLYDQLAPLCPIMLALTAASPIYRGYLTESDCRWNVISSSVDCRTEEERGLAPLDQQKFRIAKSRYDSIDSYLSPEGAKYNDVPLTYDEKVYQRLVEGGIDHLLAQHVAHLFIRDTVSLFSEKVHQNDNEDTDHFENIQSTNWQTMRFKPPPPNSSIGWRVEFRPCEAQISDFENAAIVCFVVLLTRVILSYQLNFLTPISKVDENMQTAQKRDACRKEKFWFRKSSKTTEQRAAKAQAQAQAQAKAQAQTNGKATLNGNGLANGNGNGSENSDQEEQQPLTNGSAKMNGHGSGTTNGTNGSSNGSSNGTDSDHTDTDDEENELFQLLSINEIFNGKPNVFPGLVPLIRSYLQSMEVDTDTHCTIEQYLRFIQKRAAGELITTATWMREQVLSHPDYKQDSVVSERINYDLLKRIQGIQEGKQVEPALLGQDYHSKTKTKDFIPPALQKQLAKNGCCEEK.
CBMOAB-77692FYA	Monoclonal	Zebrafish (Danio rerio)	WB, ELISA	MO77692FYA		100 µg	Inquiry
Protein Refseq: The length of the protein is 631 amino acids long. The sequence is show below: MGLLSQGSPLNWEETKKHADHVRKHGILQFLNIYNKVKDRQKDVLKWGDEVEYMLVNMDDQNEKARLVLNGKEVLEILQEKGENINPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTVEDNMGKRRREASSVLKKNETLLTVTAFPRLGCPGFTLPEYKPTPVEKGVSKSLFFPDEAINRHPRFSTLTRNIRHRRGEKVVINVPIFKDINTPSPFMEVFPEDDGEAARGAKPDHIYMDAMGFGMGNCCLQVTFQACSISEARYLYDQLATFCPIVMALSAASPFYRGFVSDIDCRWGVISASVDDRTREERGLESLKNNKFRIHKSRYDSIDSYLSCCGEKYNDIELTIDEDINKQLLDAGIDKLLAQHIAHLFIRDPLSLFQEKIHLDDENESDHFENIQSTNWQTMRFKPPPPNSEIGWRVEFRPMEVQLTDFENSAYVVFIVLLTRVILSYKLDFLIPLSKVDENMKVAQKRNAVQEGMFYFRKDVFKGCTPVLDRPGAAQNGLETETNDGEEFILMSIDTIINGKEGVFHGLIPMLNSYLENMEVDVDTRCTILNYLKLIKKRASGDLMTMAKWMREFVAKHPQYKQDSVITDKINYDLLHKCDRIAKGEEKCPELIGEPVNRGK.
MO-AB-03846H	Monoclonal	Frog (Xenopus laevis)	WB, ELISA	MO03846C		100 µg	Inquiry
Protein Refseq: The length of the protein is 637 amino acids long. The sequence is show below: MGLLSHGSPLSWEETKKYADHVRQHGIIQFLHIYHKLKERQKDVLKWGDEVEYMLVSFDHSNKKARLLLKGGEILDTLQNRGEKINPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTVEDNMRKRRQEATSLLLENNSLCSITTFPRLGCPGFTMPEFPPTPVEQGASKSLFFPDQAINKHPRFSTLTRNIRHRRGEKVAINVPIFKDQNTPSPFIERFPNVSDSEAVAAKPDHIYMDAMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIMMALSAAAPFYRGYVSDIDCRWGVISASVDDRTKEERGLEPLKNNKYRISKSRYDSIDSYLSKCGEKYNDIELTIDKEIYTQLITEGIDHLLAQHIAHLFIRDPLTLFEENIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDIGWRVEFRPVEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKMAQKRDAVRQGMFYFRKDISKAGIAVVDGCCSTQNGMESDPEECTLMSIDTIINGKEGVFPGLIPILNSYLENMEVDVDTRCTILNYLKLIKKRASGELMTCARWMREFVTSHPEYKKDSVITDKINYDLLVKCNQIANDQTACPELLGVTVNKSKPIGSQSVLV.
MO-AB-12937R	Monoclonal	Cattle (Bos taurus)	WB, ELISA	MO12937R		100 µg	Inquiry
Protein Refseq: The length of the protein is 605 amino acids long. The sequence is show below: MGLLSQGSPLSWEETQRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDHEKKKAQLVLSGEELLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTVEDNMRKRRKEATSLLGENQALCTITSFPRLGCPGFTLPEFKPNPVEGGASKSLFFPDEAINKHPRFSTLTRNIRHRRGEKVVINVPTPHLPKDHPGPAQVTFQACSISEARYLYDQLATICPIVMALSAASPFYR.
MO-AB-17936W	Monoclonal	Chimpanzee (Pan troglodytes)	WB, ELISA	MO17936W		100 µg	Inquiry
Protein Refseq: The length of the protein is 637 amino acids long. The sequence is show below: MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDHENKKVRLVLSGEKVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTVEANMRKRRKEATSILEENQALCTITSFPRLGCPGFTLPEVKPNPVEGGASKSLFFPDEAINKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPEDDEASRASKPDHIYMDAMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVISASVDDRTREERGLEPLKNNNYRISKSRYDSIDSYLSKCGEKYNDIDLTIDKEIYEQLLQEGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDIGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVLQGMFYFRKDICKGGNAVVDGCGKAQNSTELAAEEYTLMSIDTIINGKEGVFPGLIPILNSYLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIANHPDYKQDSVITDEMNYSLILKCNQIANELCECPELLGSAFRKVKYSGSKTDSSN.
MO-AB-55913W	Monoclonal	Marmoset	WB, ELISA	MO55913W		100 µg	Inquiry
Protein Refseq: The length of the protein is 637 amino acids long. The sequence is show below: MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDHENKKVRLVLSGEKVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTVEANMRKRRKEATSVLEENQAVCTITSFPRLGCPGFTLPEFKPNPVEGGASKSLFFPDEAINKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPEGDEASRSSKPDHIYMDAMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVISASVDDRTREERGLEPLKNNNYRISKSRYDSIDSYLSKCGEKYNDIDLTIDKEIYEQLLQEGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDIGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVLQGMFYFRKDICKGGNAVVDGCGKAQNSMELAAEEYTLMSIDTIINGKEGVFPGLIPILNCYLENMEVDVDTRCSILNYLKLIKKRASGELMTVAKWMREFIGNHPDYKQDSVITDEMNYSLILKCNQIANELCECPELLGSAFRKVKYSGSKTDSSN.

Specifications

Host species	Mouse (Mus musculus)
Species Reactivity	Fruit fly (Drosophila melanogaster), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Marmoset, Zebrafish (Danio rerio)
Clone	MO17302FYA
Specificity	This antibody binds to fruit fly Gclc.
Format	Liquid or Lyophilized
Storage	Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use
Purity	> 90% was determined by SDS-PAGE
Purification	Purified with Protein A or G affinity chromatography
Cellular Localization	Nucleus; Other locations

Application Information

Application	WB, ELISA
Application Notes	ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

Introduction	Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.
Product Overview	Mouse Anti-D. melanogaster Gclc Antibody is a mouse antibody against Gclc. It can be used for Gclc detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative Names	Glutamate--cysteine ligase; EC 6.3.2.2; Gamma-ECS; GCS; Gamma-glutamylcysteine synthetase; Gclc; GCSh
UniProt ID	Q9W3K5
Protein Refseq	The length of the protein is 717 amino acids long. The sequence is show below: MGLLSEGSPLSWEETKALADHVREHGVNQFINLYHRLKDRQGDILKWGDEVEYIIVKFDDEQKVARVALRAQDLLAQLNEKELADPNGVKSLWRPEYGAYMIEGTPGKPFGGLMAHFNLVEANMRYRREEVTELLAKDECVMSITNFPRLGAPNFTYPLAQPRPEDPLSSARSLYFPDEAIFPGHPRFKTLTRNIRKRRGEKVSIKLKVFKDTKTKLPVEGAPPGEPDVVLLDAMGFGMGCCCLQLTFQACNITEARRLYDQLAPLCPIMLALTAASPIYRGYLTESDCRWNVISSSVDCRTEEERGLAPLDQQKFRIAKSRYDSIDSYLSPEGAKYNDVPLTYDEKVYQRLVEGGIDHLLAQHVAHLFIRDTVSLFSEKVHQNDNEDTDHFENIQSTNWQTMRFKPPPPNSSIGWRVEFRPCEAQISDFENAAIVCFVVLLTRVILSYQLNFLTPISKVDENMQTAQKRDACRKEKFWFRKSSKTTEQRAAKAQAQAQAQAKAQAQTNGKATLNGNGLANGNGNGSENSDQEEQQPLTNGSAKMNGHGSGTTNGTNGSSNGSSNGTDSDHTDTDDEENELFQLLSINEIFNGKPNVFPGLVPLIRSYLQSMEVDTDTHCTIEQYLRFIQKRAAGELITTATWMREQVLSHPDYKQDSVVSERINYDLLKRIQGIQEGKQVEPALLGQDYHSKTKTKDFIPPALQKQLAKNGCCEEK.

For Research Use Only | Not For Clinical Use.

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