Mouse Anti-D. melanogaster Mrpl21 Antibody (CBMOAB-24698FYA)


Cat: CBMOAB-24698FYA
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFruit fly (Drosophila melanogaster)
CloneMO24698FYA
SpecificityThis antibody binds to fruit fly Mrpl21.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationMitochondrion

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionMammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Multiple transcript variants encoding different isoforms were identified through sequence analysis although some may be subject to nonsense-mediated decay (NMD).
Product OverviewMouse Anti-D. melanogaster Mrpl21 Antibody is a mouse antibody against Mrpl21. It can be used for Mrpl21 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesMitochondrial ribosomal protein L21, isoform A; Mitochondrial ribosomal protein L21, isoform B; Mitochondrial ribosomal protein L21, isoform C; RH57745p1; mRpL21; mRpL21-RA
UniProt IDQ9VVX4
Protein RefseqThe length of the protein is 201 amino acids long.
The sequence is show below: MSFLAQTMRQMLRHVPNRSLLTAGAMRPLSISPVIGQQNKPATESVDLSAIAKDQQKECLSICERINRQVQKSEQGRLFAVVHLCGKQFKVTPGDIILVEGYWPPTIGDEISLDKVLLAGARDFTLVGRPILEPGLILVKATVVEKTLSHTKTHFRKKRRKQYMRINFQRSPHTMVRINSIELARPVDGNGEGESSSRRLF.
For Research Use Only | Not For Clinical Use.
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