Mouse Anti-D. melanogaster Pex3 Antibody (CBMOAB-27483FYA)


Cat: CBMOAB-27483FYA
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFruit fly (Drosophila melanogaster)
CloneMO27483FYA
SpecificityThis antibody binds to fruit fly Pex3.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationPeroxisome

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe product of this gene is involved in peroxisome biosynthesis and integrity. It assembles membrane vesicles before the matrix proteins are translocated. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause Zellweger syndrome (ZWS).
Product OverviewMouse Anti-D. melanogaster Pex3 Antibody is a mouse antibody against Pex3. It can be used for Pex3 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesLD41491p; Peroxin 3, isoform A; Peroxin 3, isoform B; Pex3
UniProt IDQ9VUL8
Protein RefseqThe length of the protein is 385 amino acids long.
The sequence is show below: MLSRLQDFLSRHRRKFIVTGVLVGGTIFAARYAQRRFVEFQEKQAREFFERTRRTTHFESTEKTCNQVILGMGEEMCQAVLRECSTDELLEQLRQNPKNKLELWEDMKIVAFTRLATYVYASSMLVIALRVQLNLLGGYIYRDIMTEQKQVTDELKQQYLSLIRHFITDSGIRDLARYIRTQVIAVTKTIPLSEQLSLSDLEQLFWSLQMAINADTRRDPNSRMSKYLLPSQNPSHSPLLQKMVNETLDLLESEDAVGVCSHNVSRGFVLACDAIAESMGETLQHLPQAKVQTQQEQSVKFNQAGSLGASTSKSQNGLENNNLLNINRVLLALAKLIPIISGLTSRGFDTTSRPHNLPTQLLTFYVVAEKTKTLGANVYESFSSA.
For Research Use Only | Not For Clinical Use.
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