AibGenesis™ Mouse Anti-D. melanogaster Pgrp-Lc Antibody (CBMOAB-27552FYA)
Cat: CBMOAB-27552FYA
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Specifications
- Application Information
- Target
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Fruit fly (Drosophila melanogaster) |
| Clone | MO27552FYA |
| Specificity | This antibody binds to fruit fly Pgrp-Lc. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Plasma Membrane; Other locations |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Major activator of the imd/Relish pathway and is likely to encode a pattern recognition molecule for the humoral immune response (PubMed:11872802, PubMed:22022271). Required for Relish processing and nuclear translocation following proteolytic cleavage (PubMed:11872802). Involved in the response to lipopolysaccharide (LPS) and peptidoglycan of Gram-negative bacteria (PubMed:11872802). The different isoforms probably display different recognition capabilities to various microbial patterns (PubMed:12777387, PubMed:16006509). (From uniprot, under CC BY 4.0) |
| Product Overview | Mouse Anti-D. melanogaster Pgrp-Lc Antibody is a mouse antibody against Pgrp-Lc. It can be used for Pgrp-Lc detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Peptidoglycan-recognition protein LC; Immune response deficient 7 protein; PGRP-LC; ird7 PGRPLC |
| UniProt ID | Q9GNK5 |
| Protein Refseq | The length of the protein is 520 amino acids long. The sequence is show below: MPFSNETEMSQCSNAKRRVNDPLTGPKNCSTSSTDSGVILNDNVAAFRPEKETKDRGTGEGQFQSKSEEKTESKRISVEHTVNITTENVGKTSSPAVSIRSTTISVVSIDDNAIDSSSIDSDSEAEAEDYTVQKLGHQVTYPPNSSHLRDLNQGLTVISRHVAPGEAAVPPPNPLEAGIVAKQILNGNLAVATPTSPAGGATQGIGSIALTNSTDVTFGDKHFYEGPVTIQQFLIDNRDKWKPGEGPAGGQDNPAFNGGPSTNGSAPGSKHEDPAQTPPICPFLPNTVGRKAVTVTVVFVTLTFLLGIVLATTTNLFGKTLNQSKIRDDDDYRQNIPINSTIDLDNIGGGLILRFVERQQWLAQPPQKEIPDLELPVGLVIALPTNSENCSTQAICVLRVRLLQTYDIESSQKCDIAYNFLIGGDGNVYVGRGWNKMGAHMNNINYDSQSLSFAYIGSFKTIQPSAKQLSVTRLLLERGVKLGKIAPSYRFTASSKLMPSVTDFKADALYASFANWTHWS. |
For Research Use Only | Not For Clinical Use.
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