Mouse Anti-D. melanogaster Yt521-B Antibody (CBMOAB-34571FYA)


Cat: CBMOAB-34571FYA
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  • Specifications
  • Application Information
  • Target

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFruit fly (Drosophila melanogaster)
CloneMO34571FYA
SpecificityThis antibody binds to fruit fly Yt521-B.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionRegulator of alternative splicing that specifically recognizes and binds N6-methyladenosine (m6A)-containing RNAs (PubMed:27919077, PubMed:27919081, PubMed:28675155). Acts by acting as a reader of m6A methylation (PubMed:27919077, PubMed:27919081). Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physiognomy (PubMed:27919077, PubMed:27919081, PubMed:28675155). M6A methylation is also required for neuronal functions (PubMed:27919077). (From uniprot, under CC BY 4.0)
Product OverviewMouse Anti-D. melanogaster Yt521-B Antibody is a mouse antibody against Yt521-B. It can be used for Yt521-B detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesBcDNA.GH01918; YT521-B; BcDNA.GH01918
UniProt IDQ9Y172
Protein RefseqThe length of the protein is 721 amino acids long.
The sequence is show below: MPRAARKQTLPMREMADLDAVHLGLDENEADIAEELQDFEFNTRSEASESNGGDSSDSEPSISSVSTATSSLAGSSKRKTKKPAKQSPQPAVETKSSKSSAKNKAKREPTPEELNGGKKKKRTDSGTKKTTSSEASDKVKSKSPDTEDRQPSAKKSRTKIPSNANDSAGHKSDLSEAEDEKPSLPTLESDSESSDSDSGTQHKRNGGNGGGNGRGKPSSKSSTPEKDSVGGGTHSHSQKGYDYMTKLNYLFRDTRFFLIKSNNSDNVQLSKNKSVWATLPQNDANLNQAFKEARNVLLIFSVNESGKFAGFARMAAPSRRDIPQVAWVLPPSISPKALGGVIELDWICRKELSFNATLHLHNTWNEGKPVKIGRDGQEIEPKIGGELCRLFPEDEQIELTPILKKSKETARVMREKGIHVIYKPPRSLSSRGHGGGGRGGGRGSNHDHLGPMRHKRSYHGAPHHRPYRHHHGMGLPPGGGFKRSGSPYRQMGGAAGAPPGGPGDMAMPSWERYMSSAAAAEAYVADYMRNMHGQLPPLPFVPPFAQLPIPGAGAGAAGALPPGAAAAMYEQLPPPVRYYDGPGAPPLPDYPPPQRPPPPGFDKAPSYEEFAAWKNAGLPTVPPPGFPVYGGAANGGGNGAGGLAAARAAAAGGGMGAGGGSGGGMGGPGGYRNRDGNNGSAGGRRREYGNRSGGGGSSRDSRPFRERGGGGGQRSYRDNRR.
For Research Use Only | Not For Clinical Use.
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