Mouse Anti-D2HGDH Antibody (CBMOAB-27341FYC)

Cat: CBMOAB-27341FYC

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Lot Number

Product List
Specifications
Application Information
Target

Sub Cat	Clonality	Species Reactivity	Application	Clone	Conjugate	Size
CBMOAB-27341FYC	Monoclonal	A. thaliana (Arabidopsis thaliana), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Marmoset, Rhesus (Macaca mulatta), Rice (Oryza), Zebrafish (Danio rerio)	WB, ELISA	MO27341FC		100 µg	Inquiry
Protein Refseq: The length of the protein is 559 amino acids long. The sequence is show below: MMMQKLRRSGEFIRFGCKSLISSRPNKDSVSRSVSGFVNHYKSKGKLFELSDGNYKTELHHPCISRNVGMLLQQYKCFGSSAASLIQRNPLFSSLDSKDVSYFKEILGEKNVVEDKERLETANTDWMHKYKGSSKLMLLPKNTQEVSQILEYCDSRRLAVVPQGGNTGLVGGSVPVFDEVIVNVGLMNKILSFDEVSGVLVCEAGCILENLATFLDTKGFIMPLDLGAKGSCHIGGNVSTNAGGLRLIRYGSLHGTVLGLEAVTANGNVLDMLGTLRKDNTGYDLKHLFIGSEGSLGIVTKVSILTQPKLSSVNLAFIACKDYLSCQKLLVEAKRNLGEILSAFEFLDNNSMDLVLNHLDGVRNPVSSSENFYILIETTGSDETNDREKLEAFLLKSLEKGLVSDGVIAQDINQASSFWRIREGITEALQKAGAVYKYDLSLPVEEIYNIVNDLRGRLGDLANVMGYGHLGDGNLHLNISAAEYNDKLLGLIEPYVYEWTSKHRGSISAEHGLGVMKANEIFYSKSPETVALMASIKKLLDPKGILNPYKVLPHSLFSN.
CBMOAB-40357FYA	Monoclonal	Rhesus (Macaca mulatta)	WB, ELISA	MO40357FYA		100 µg	Inquiry
Protein Refseq: The length of the protein is 505 amino acids long. The sequence is show below: APGAAGSWGRPVGPLARRGCCSAPGTPEVPLTRERYPVRRLPFSTVSEQDLAAFERIVPGGVVTDPEALQAPNVDWIRTLRGSSKVLLRPRTSEEVSHILRHCHERNLAVNPQGGNTGMVGGSVPVFDEIILSTARMNKVLSFHSVSGILVCQAGCVLEELSHYVEERDFIMPLDLGAKGSCHIGGNVATNAGGLRFLRYGSLHGTVLGLEVVLADGTILDCLTSLRKDNTGYDLKQLFIGSEGTLGVITAVSILCPPKPRAVNVAFLGCPGFAEVLQTFSTCKGMLGEILSAFEFMDAVCMQLVGRYLHLASPVQESPFYVLIETSGSNAGHDAEKLGSFLEHALGSGLVTDGTMATDQTKVKMLWALRERIAEALSRDGYVYKYDLSLPVERLYDIVTDVRARLGPHAKHVVGYGHLGDGNLHLNVTAEAFSPSLLGALEPHVYEWTARQQGSVSAEHGVGFRKRDVLGYSKPPEALQLMQQLKALLDPKGILNPYKTLPSQA.
CBMOAB-72836FYA	Monoclonal	Zebrafish (Danio rerio)	WB, ELISA	MO72836FYA		100 µg	Inquiry
Protein Refseq: The length of the protein is 533 amino acids long. The sequence is show below: MGLFQKCSRLSLRSSYMWSVCPQYSIAVTARETPDRALIVHWTQHRDVHNSRRLGANPANPSAAPPRLPFSRVTQEDLSFFRALLPGRTITDPDLLKSSNVDWLKTVQGSSDVLLRPKTTEEVSQILRYCNERNLAVCPQGGNTGLVGGSVPVFDEIILSTSLMNQVFAFDNISGILTCQAGCVLENLSHYLEERDFIMPLDLGAKGSCHIGGNVSTNAGGLRLLRYGSLRGTVLGLEVVLADGRVLNCLATLRKDNTGYDLKQLFIGSEGTLGVITAVSILCPRKPKAVNVAFLGCSSFQQLLETFQCCRGMLGEILSAFEFLDASCMNLLEKHLKLTNPITECPFYIVIETAGSNATHDEEKLHQFLEEVMTSSLVTDGTVATEATKIKALWSLRERVTEALTHEGYTYKYDISLPVEKIYDLVQDMRRHLGGMAKNVVGYGHVGDGNLHLNITSPSKDFALLAAIEPYVYEWTSQWKGSISAEHGLGLKKRNYIYYSKPSEAVALMGSIKAMLDPKGILNPYKTLPDNIN.
CBMOAB-22470FYB	Monoclonal	Rice (Oryza)	WB, ELISA	MO22470FYB		100 µg	Inquiry
Protein Refseq: The length of the protein is 559 amino acids long. The sequence is show below: MARRAAAGLLRRHLGPLAAGETLQARGMYPKQYGAANHAFSRFYSIQGQQRSLYGFRTNVETDDTQQSARMNFEVQKRSFSSAAAHVQRNPAYSVLNSDDVSYFKSILGDSGVVQDEDRVSVANMDWMGKYKGSSQLLLLPKSTAEVSKILSYCNSRRLAVVPQGGNTGLVGGSVPVYDEVIISLGGMDKIITFDNVNGILTCEAGCVLENLSSYVENKGFIMPLDLGAKGSCHIGGNISTNAGGLRFIRYGSLHGSVLGLEVVLADGTVLDMLTTLRKDNTGYDLKHLFIGSEGSLGIVTKIAILTPAKLPSTNVAFLSCNDYISCQKLLLAARRSLGEILSAFEFMDRHCINLAMKYLEGVHNPLPVSPFNFYVLIETTGSDESYDKAKLEAFLLRSMEDGLVADGVIAQDISQASNFWRIREGISEASVKVGAVYKYDLSIPVEKLYDIVEEMRSRVGDMGQVLGYGHLGDGNLHLNILSTKYSDKMLAQIEPFVYEWTSKQRGSISAEHGLGLMKAEKIHYSKSSEAVQLMASIKKLLDPNSILNPYKVLPQSVL.
MO-AB-20099W	Monoclonal	Chimpanzee (Pan troglodytes)	WB, ELISA	MO20099W		100 µg	Inquiry
Protein Refseq: The length of the protein is 521 amino acids long. The sequence is show below: MLPRRPLAWPAWLLRGAPGAAGSWGRPVGPLARRGCCSAPGIPEVPLTRERYPVRRLPFSTVSKQDLAAFERIVPGGVITDPEALQAPNVDWLRTLRGCSKVLLRPRTSEEVSHILRHCHERNLAVNPQGGNTGMVGGSVPVFDEIILSTARMNRVLSFHSVSGILVCQAGCVLEELSRYVEERDFIMPLDLGAKGSCHIGGNVATNAGGLRFLRYGSLHGTVLGLEVVLADGTVLDCLTSLRKDNTGYDLKQLFIGSEGTLGIITAVSILCPPKPRAVNVAFLGCPGFAEVLQTFSTCKGMLGEILSAFEFMDAVCMQLVGRHLHLASPVQESPFYVLIETSGSNAGHDAEKLGRFLEHVLGSGLVTDGTMATDQRKVKMLWALRERITEALSRDGYVYKYDLSLPVERLYDIVTDLRARLGPHAKHVVGYGHLGDGNLHLNVTAEAFSPSLLAALEPHVYEWTAGQQGSVSAEHGVGFRKRDVLGYSKPPGALQLMQQLKALLDPKGILNPYKTLPSQA.
MO-AB-53876W	Monoclonal	Marmoset	WB, ELISA	MO53876W		100 µg	Inquiry
Protein Refseq: The length of the protein is 529 amino acids long. The sequence is show below: MLPRRPLAWLAWVFRGPPGPRGACAPGAAGSWGRRVGPLPRRGCCTAPGTPEVPLTQERYPVRRLPFSTVSEQDLAAFERIVPGGVVTDPEALRAPNVDWLRTLRGCSKVLLRPRTSEEVSSILRYCHERNLAVNPQGGNTGMVGGSVPVFDEIILSTALMNRVLSFHSVSGILVCQAGCILEELSRYVEERDFIMPLDLGAKGSCHIGGNVATNAGGLRFLRYGSLHGTVLGLEVVLADGTVLDCLTSLRKDNTGYDLKQLFIGSEGTLGVITAVSILCPPKPRAVNVAFLGCPGFAEVLQTFSTCKGMLGEILSAFEFMDAECMQLVGRHLHLASPVQESPFYVLIETSGSNAGHDAEKLGSFLEHALGSGLVTDGTMATDQRKVKMLWALRERITEALSRDGYVYKYDVSLPVERLYDIVTDLRARLGPHTKHVVGYGHLGDGNLHLNVTAEAFSPSLLGALEPHVYEWTARQQGSVSAEHGVGFRKRDVLGYSKPHEALKLMQQLKALLDPKGILNPYKTLPSQA.
MO-AB-11161R	Monoclonal	Cattle (Bos taurus)	WB, ELISA	MO11161R		100 µg	Inquiry
Protein Refseq: The length of the protein is 544 amino acids long. The sequence is show below: MMMPRLVPRWPAWLFCWRAACIQGASVRQKMWAGPSKIPGLGGPRGAWGTSPLVPRGSCSASSRTPEVTLTPERYPVQRLPFSVVSEDDLAALERVVPGRVITDPEELEPPNVDWLRTVRGSSKVLLRPRTTQEVAHILRYCHERNLAVNPQGGNTGMVGGSTPVFDEIILSTALMNQVLSFHDVSGVLVCQAGCVLEALSQYVEERGFIMPLDLGAKGSCHIGGNVATNAGGLRVLRYGSLRGTVLGLEVVLAD.
MO-DKB-00206W	Polyclonal	Zebrafish (Danio rerio)	ELISA			100 µg	Inquiry

Specifications

Host species	Mouse (Mus musculus)
Species Reactivity	A. thaliana (Arabidopsis thaliana), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Marmoset, Rhesus (Macaca mulatta), Rice (Oryza), Zebrafish (Danio rerio)
Clone	MO27341FC
Specificity	This antibody binds to Arabidopsis D2HGDH.
Format	Liquid or Lyophilized
Storage	Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use
Purity	> 90% was determined by SDS-PAGE
Purification	Purified with Protein A or G affinity chromatography
Cellular Localization	Mitochondrion; Plasma Membrane

Application Information

Application	WB, ELISA
Application Notes	ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

Introduction	This gene encodes D-2hydroxyglutarate dehydrogenase, a mitochondrial enzyme belonging to the FAD-binding oxidoreductase/transferase type 4 family. This enzyme, which is most active in liver and kidney but also active in heart and brain, converts D-2-hydroxyglutarate to 2-ketoglutarate. Mutations in this gene are present in D-2-hydroxyglutaric aciduria, a rare recessive neurometabolic disorder causing developmental delay, epilepsy, hypotonia, and dysmorphic features. D2HGDH (D-2-Hydroxyglutarate Dehydrogenase) is a Protein Coding gene. Diseases associated with D2HGDH include D-2-Hydroxyglutaric Aciduria 1 and 2-Hydroxyglutaric Aciduria. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. and Pyruvate metabolism and Citric Acid (TCA) cycle. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and oxidoreductase activity, acting on CH-OH group of donors. Catalyzes the oxidation of D-2-hydroxyglutarate to alpha-ketoglutarate.
Product Overview	Mouse Anti-Arabidopsis D2HGDH Antibody is a mouse antibody against D2HGDH. It can be used for D2HGDH detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative Names	D-2-Hydroxyglutarate Dehydrogenase; D2HGD; D-2-Hydroxyglutarate Dehydrogenase, Mitochondrial; EC 1.1.99.-; EC 1.1.99
UniProt ID	O23240
Protein Refseq	The length of the protein is 559 amino acids long. The sequence is show below: MMMQKLRRSGEFIRFGCKSLISSRPNKDSVSRSVSGFVNHYKSKGKLFELSDGNYKTELHHPCISRNVGMLLQQYKCFGSSAASLIQRNPLFSSLDSKDVSYFKEILGEKNVVEDKERLETANTDWMHKYKGSSKLMLLPKNTQEVSQILEYCDSRRLAVVPQGGNTGLVGGSVPVFDEVIVNVGLMNKILSFDEVSGVLVCEAGCILENLATFLDTKGFIMPLDLGAKGSCHIGGNVSTNAGGLRLIRYGSLHGTVLGLEAVTANGNVLDMLGTLRKDNTGYDLKHLFIGSEGSLGIVTKVSILTQPKLSSVNLAFIACKDYLSCQKLLVEAKRNLGEILSAFEFLDNNSMDLVLNHLDGVRNPVSSSENFYILIETTGSDETNDREKLEAFLLKSLEKGLVSDGVIAQDINQASSFWRIREGITEALQKAGAVYKYDLSLPVEEIYNIVNDLRGRLGDLANVMGYGHLGDGNLHLNISAAEYNDKLLGLIEPYVYEWTSKHRGSISAEHGLGVMKANEIFYSKSPETVALMASIKKLLDPKGILNPYKVLPHSLFSN.

For Research Use Only | Not For Clinical Use.

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