Rabbit Anti-Dact1 (AA 725-775) Antibody (Cat MO-DKB-03161W)


Cat: MO-DKB-03161W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Chicken (Gallus gallus), Primate, Frog (Xenopus), Zebrafish (Danio rerio), Cattle (Bos taurus), Dog (Canis lupus familiaris)
SpecificityBased on the sequence homology of the immunogen (76%), the antibody may cross-react with Dact2
ImmunogenA portion of amino acids 725-775 of human Dapper homolog 1 is used as an antibody immunogen.
EpitopeAA 725-775
FormatLiquid or Lyophilized
BufferPBS, 0.05% BSA
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationProtein G purified

Application Information

ApplicationWB, IHC, IHC-P
Application NotesWestern Blot: 0.5-1 ug/mL
Immunohistochemistry-Paraffin: 10 ug/mL
The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene belongs to the dapper family, characterized by the presence of PDZ-binding motif at the C-terminus. It interacts with, and positively regulates dishevelled-mediated signaling pathways during development. Depletion of this mRNA from xenopus embryos resulted in loss of notochord and head structures, and mice lacking this gene died shortly after birth from severe posterior malformations. Alternatively spliced transcript variants have been found for this gene.
Product OverviewThis product is a Rabbit antibody against the Dact1. It can be used for Dact1 detection in Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.
Alternative NamesDact1 protein; Dapper homolog 1, antagonist of beta-catenin (Xenopus); dact
UniProt IDA0JPE3
For Research Use Only | Not For Clinical Use.
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