Mouse Anti-DHCR7 Antibody (CBMOAB-02647HCB)
Cat: CBMOAB-02647HCB
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
| Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
| CBMOAB-02647HCB | Monoclonal | C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Marmoset, Rhesus (Macaca mulatta), Zebrafish (Danio rerio) | WB, ELISA | MO02647HB | 100 µg | ||
| CBMOAB-40716FYA | Monoclonal | Rhesus (Macaca mulatta) | WB, ELISA | MO40716FYA | 100 µg | ||
| CBMOAB-73430FYA | Monoclonal | Zebrafish (Danio rerio) | WB, ELISA | MO73430FYA | 100 µg | ||
| MO-AB-02968H | Monoclonal | Frog (Xenopus laevis) | WB, ELISA | MO02968C | 100 µg | ||
| MO-AB-10726W | Monoclonal | Chimpanzee (Pan troglodytes) | WB, ELISA | MO10726W | 100 µg | ||
| MO-AB-11409R | Monoclonal | Cattle (Bos taurus) | WB, ELISA | MO11409R | 100 µg | ||
| MO-AB-54167W | Monoclonal | Marmoset | WB, ELISA | MO54167W | 100 µg |
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Frog (Xenopus laevis), Marmoset, Rhesus (Macaca mulatta), Zebrafish (Danio rerio) |
| Clone | MO02647HB |
| Specificity | This antibody binds to C. elegans DHCR7. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Endoplasmic reticulum |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | This gene encodes an enzyme that removes the C(7-8) double bond in the B ring of sterols and catalyzes the conversion of 7-dehydrocholesterol to cholesterol. This gene is ubiquitously expressed and its transmembrane protein localizes to the endoplasmic reticulum membrane and nuclear outer membrane. Mutations in this gene cause Smith-Lemli-Opitz syndrome (SLOS); a syndrome that is metabolically characterized by reduced serum cholesterol levels and elevated serum 7-dehydrocholesterol levels and phenotypically characterized by cognitive disability, facial dysmorphism, syndactyly of second and third toes, and holoprosencephaly in severe cases to minimal physical abnormalities and near-normal intelligence in mild cases. Alternative splicing results in multiple transcript variants that encode the same protein. |
| Product Overview | Mouse Anti-C. elegans DHCR7 Antibody is a mouse antibody against DHCR7. It can be used for DHCR7 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Protein DHCR-7; Sterol reductase; dhcr-7 |
| UniProt ID | G5ED82 |
| Protein Refseq | The length of the protein is 457 amino acids long. The sequence is show below: MKELNRIRRSSLGGSTSSLTRRSSISQKDIQALQETLQKQQKVSAQMVLALLIIVPPATFFLFYSISIHTGLFVPTITALFLRFPLVLQCVPPVWDTVAWKFSAVHCAIQLIFYWVLPHDQALVMSSAGDQMREVNSFFSCILTCLLYVLGASAGVYRGDLVYLHFNSIILIFAIFAVLIWAALIATYHFGTGNSVTTISEFWFGIENHPKILDIDLKSFIRTRFTFVIWPLFVISAMYFHKITYGQISTSLVCLSSVQLLYIFQFHWNEDLFLNSLDSKRCDFGFYRIWADFVLGPIIYTSPVTILVATNRSVGVISNCLFCAVAIGSMVFTAKCDRQKYEFRKSKGTLKVGGVDAFFISAKYRTDSGDANTNLLLGSGHWGVCRHPNYASEAITFAAFSAFQGFPSTIAHIPSLFVILFLVARAFTDENRCLIKYGQYWAQYCSKVKYRFLPGVF. |
For Research Use Only | Not For Clinical Use.
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