Mouse Anti-Dog Abcb11 Antibody (MO-AB-28780W)


Cat: MO-AB-28780W
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityDog (Canis lupus familiaris)
CloneMO28780W
SpecificityThis antibody binds to Dog Abcb11.
FormatLyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy.
Product OverviewMouse Anti-Dog Abcb11 (clone MO28780W) Antibody (MO-AB-28780W) is a mouse antibody against Abcb11. It can be used for Abcb11 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesATP-binding cassette protein B11; Abcb11
UniProt IDB8K1W2
Protein RefseqThe length of the protein is 1325 amino acids long.
The sequence is show below: MSDAVILRSVKKFGEDNYGFESSTFYNNDKNSGLQDERKGDSSQVGFFQLFRFSSTTDIWLMFVGSLCAFLHGLSHPGVLLIFGTMTDVFIAYDTELQELKIPGKACVNNTIVWINSSLNQNVTNGTQCGLLDIESEMIKFASYYAGIALLVLITGYIQICFWVIAAARQIQKMRKISFRKVMRMEIGWFDCNSVGELNTRFSDDINRVNDAIADQMPIFIQRMTTSICGFLLGFYQGWKLTLVIISVSPLIGIGAAIIGLSVSKFTDYELKAYAKAGSVADEVISSMRTVAAFGGEKKEVERYEKNLVFAQRWGIRKGIVMGFFTGFMWCLIFLCYALAFWYGSKLVLEDGEYTAGTLVQIFLSILLGALNLGNASSCLEAFATGRAAATSIFHTIDRKPIIDCMSEDGYKLDRIKGEIEFHNVTFHYPSRPEVKILNNLSMVIKSGEMTAVVGSSGSGKSTALQLIQRFYDPSEGMVTLDGHDIRSLNIQWLRTQIGIVEQEPVLFSTTIAENIRYGREDATMEDIVRAAKAANAYNFIMDLPEQFDTLVGEGGGQMSGGQKQRVAIARALVRNPKILLLDMATSALDNESEAMVQEALSKIQQGHTIISVAHRLSTVRAADVIIGFEHGTAVERGSHEELLERKGVYFTLVTLQSQGEPTANAEGIRGEEETDGVSLDNEQTFCRGSYQSSLRASLRQRSKSQLSYLAHEPPLAVVDHKSTYEEDRKDKDIPVEEEIEPAPVRRILKFNAPEWPYMLFGAVGAAVNGSVTPLYAFLFSQILGTFSLPDKEEQRSQINGVCLLFVAVGCVSLCTQFLQGYAFAKSGELLTKRLRKYGFRAMLGQDIGWFDDLRNSPGALTTRLATDASQVQGAAGSQIGMMVNSFTNVTVAMIIAFFFSWKLSLVIMCFFPFLALSGALQTRMLTGFATQDKEALEIAGQITNEALSNIRTVAGIGKERQFIEAFEAELEKPFKTAFRKANVYGFCFGFSQCIVFVANSASYRYGGYLIPNEGLHFSYVFRVISSVVLSATALGRASSYTPSYAKAKISAARFFQLLDRQPPIKVYSSAGEKWDNFQGQVDFVDCKFTYPSRPDTQVLNGLSVSVRPGQTLAFVGSSGCGKSTSIQLLERFYDPDQGKVMIDGHDSRKVNVQFLRSNIGIVSQEPVLFACSIMDNIKYGDNTREIPMEKVIEAAKQAQLHDFVMSLPEKYETNVGSQGSQLSRGEKQRIAIARAIVRNPKILLLDEATSALDTESEKTVQVALDKAREGRTCIVIAHRLSTIQNSDIIAVMSQGIVIEKGTHEELMAQKGAYYKLVTTGAPIS.
For Research Use Only | Not For Clinical Use.

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