Mouse Anti-Dog RP1 Antibody (MO-AB-33100W)
Cat: MO-AB-33100W
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Dog (Canis lupus familiaris) |
| Clone | MO33100W |
| Specificity | This antibody binds to Dog RP1. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Other locations; Cytoskeleton |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two doublecortin domains, which bind microtubules and regulate microtubule polymerization. The encoded protein is a photoreceptor microtubule-associated protein and is required for correct stacking of outer segment disc. This protein and the RP1L1 protein, another retinal-specific protein, play essential and synergistic roles in affecting photosensitivity and outer segment morphogenesis of rod photoreceptors. Because of its response to in vivo retinal oxygen levels, this protein was initially named ORP1 (oxygen-regulated protein-1). This protein was subsequently designated RP1 (retinitis pigmentosa 1) when it was found that mutations in this gene cause autosomal dominant retinitis pigmentosa. Mutations in this gene also cause autosomal recessive retinitis pigmentosa. Transcript variants resulted from an alternative promoter and alternative splicings have been found, which overlap the current reference sequence and has several exons upstream and downstream of the current reference sequence. However, the biological validity and full-length nature of some variants cannot be determined at this time. |
| Product Overview | Mouse Anti-Dog RP1 Antibody is a mouse antibody against RP1. It can be used for RP1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Oxygen-regulated protein 1; Retinitis pigmentosa RP1 protein homolog; RP1 |
| UniProt ID | Q8MJ04 |
| Protein Refseq | The length of the protein is 2141 amino acids long. The sequence is show below: MSETSSTSVSMIHRSFEGQGPPRHLSVMHPVVAKKISFYKSGDPQFGGVKVVVNPRSFKTFDALLDNLSRKVPLPFGVRNISTPRGRHSITRLEELEDGASYLCSHRRKVQPVDLDKARRRPRPWLSSRAISAHAQRSPPTSIGAAGAPGMLRAPRRLLVFRNGDPKIRRVVIVNRRVTQSFQAFLQHLTEVMRFPVTKLYATDGRKVPSLQAVILSSGAVVAAGREPFKPGNYDIQKYLLSARLPGTSHHVYIKGNTRSESRKMSTHVPSSPRSQIYSVSSGKMHNNDCYSDHSFASENYLALEKNDSRNLLIYPSEDDIEKSIIFNQDGTMTVEMKVRFKIKEEETIKWTTVSRASLSHNNEKCEVGCFPGRTDDQSSHLKIAACSLSADVSSLEKDNNQEVSLTEEINTRITDQETETCTSVSWENGAMDTNICTRVTQDQAKHHFYRPPTPGPKRVRQKSVRGSVTLVSETEVEEEMIRQFSYSEAREDGENKSEYHMFTHSCSKMSSVSNKPLLVQINNNEQMESSLERKKESRLLKSGAIRAGVEITNQKMLEMSHNNGSPQTISENSIVGEVIVDSLTSDNKTNIKILRPYSRTRDRFSPILADTTHSLSNDSGIDKTVSEIPALVESSTVTTRIDRLINEFAQCDLTNSANEKQTSLSVASKKKMKSQQQVINSRHQIRKIATKGILSKNKRINTGRRIAQEIILEGSDGSLKGGVVCEEDLHVSDTVIESNYCSQSDLNPVNSKNFHVNKLNTLQNPKKFQGLLAKRKSRPLTKVSLGGPTKREIGQGDKVFPHNDFRYCKNNFEDQNLFPMFNFLEQRPSDFCGPQGQAEIASWYLGGITKKNLVSKVNNSHITLKTQKKQKGDKLKSSTTVSKQQVTTRANSLGSLKKAVFPEAISHHSVQNYIQRWLQNTNPHSALQSRKSAPIYKKDRSVVSCNNNGFAGTKSHTSSGEGNNFARESNKYITKNASLTENLGKKVGKFFDKVNSEELSKDLCENQVESLNDACLLPLHENCALSQSAIDDHNTKIQVCAEKLGPEISLVYQEINVATKRHSVEAAIQVDLTEEDTSKDPLPILLLRQLQALVPSIHKTQNGITQMPGSLADIPFSSPICKSYTNVLLAWLLVLTLKGSINSFCQGDAHKTTNRASEILGLLEVLRHTAITEEADDLKAAVANLVESTTNHFGLTEKEQDMVPVGLSANCSTPNLHRVPKCVENEKTQKISSGGGHSASEHCGPEACVSELTCSCQMCIVNKTCPPKETCNLSDIFCPSDGCTVDQTPMNKACFQGEVCSLTDALSSHRACAHEENHSRKATCPIDEAYIPNKICNTSDFLIFKENTCTDNLELTEELERINKVQKDLNVLADPGCKHSFNILVSDQNISNLSYSSFPINETEPEFDKERSSVAELKNYSLKTFQGKNAYTSSDKEDSKTSEEPGSITNSMTSSERNISELESFEELENQDTDTFHMKVNAREQAAEELIQKELEASKNLQLIDGSRRNITEEEERNGIICEAIRRRLATPPSLVFCYDSKQNTEKDLNEGETKMRVKMMVKSVEIGSYSESSLDFKNDFIGPVTSDWSEFRPSSENEQPYKTSSDGPNGSCEEIVQDKDYNKGFVKRTIEKLYSKGEIIKPSFFSGSIHRSQVCPYNSVEFQCARKVDLYDCEGQSFGSSEQLSSNSSMLQKFLEEGQDKCDFNDVRANYHGGDILGHGTKQNDHNRIIRDIEEGVLIDKGKWLLKENHLLRISSPENSGLYGNADTISVDTLLNNDNEVPYSHFGNLAPDPTMAELSSSELEELSQPLELKCSYFNMPHCSDSEPFCEDLLDVQNKTCARERIPVHHAEEKANHKSERVCTSVTHGFTSAGNKVHPVSDDTIKNQPLPVNNAIHGALQEGDSLDKLYAICGQHCPILTVIIQPINEEDRGFAYCKNSDIENFLGLHLWMKVHPYLLPSNKTIFRDANNKANGRKAFIDNAFDDTFDLMDKRKLRNLKGISSLGLEEENNLKKFQLYLKKKFCVNFLHTSLLIVDNRNSDTRDSINQTNEIFEVVDENNNFLNSRFQNSRTNLNQVVRECSDFFFEMHGQTCLFYQVETSLNISNRNTVEIFYVFEDENLFIWEEESQFDLESNDEDL. |
See other products for " rp1 "
| MO-AB-07204H | Mouse Anti-Frog rp1 Antibody (MO-AB-07204H) |
| MO-AB-19443R | Mouse Anti-Cattle RP1 Antibody (MO-AB-19443R) |
| CBMOAB-56713FYA | Mouse Anti-Rhesus RP1 Antibody (CBMOAB-56713FYA) |
| CBMOAB-40295FYC | Mouse Anti-Arabidopsis RP1 Antibody (CBMOAB-40295FYC) |
| CBMOAB-96334FYA | Mouse Anti-Zebrafish rp1 Antibody (CBMOAB-96334FYA) |
For Research Use Only | Not For Clinical Use.
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