Mouse Anti-degP (NVEGSTTVNTPR) Antibody
Cat: MOXC-011W
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
| Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
| MOXC-011W | Monoclonal | E. coli, E. coli (Escherichia coli ) | WB, ELISA | XM11 | |||
| CBMOAB-0544YC | Monoclonal | E. coli (Escherichia coli ) | WB, ELISA | MO0544YC | 100 µg | ||
| MOXC-009W | Monoclonal | E. coli | WB, ELISA | XM09 | |||
| MOXC-010W | Monoclonal | E. coli | WB, ELISA | XM10 |
Specifications
| Host species | Mouse |
| Species Reactivity | E. coli, E. coli (Escherichia coli ) |
| Clone | XM11 |
| Immunogen | E. coli degP (NVEGSTTVNTPR) |
| Epitope | NVEGSTTVNTPR |
| Format | Liquid or Lyophilized |
| Buffer | 0.05 M Tris-HCl, pH 7.4, 100 mM glycine |
| Regulatory Status | For Research Use Only |
| Shipping | Gel Pack |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Protein A or G |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | DegP acts as a chaperone at low temperatures but switches to a peptidase (heat shock protein) at higher temperatures (PubMed:10319814). Degrades transiently denatured and unfolded or misfolded proteins which accumulate in the periplasm following heat shock or other stress conditions (PubMed:16303867). DegP is efficient with Val-Xaa and Ile-Xaa peptide bonds, suggesting a preference for beta-branched side chain amino acids (PubMed:8830688). Only unfolded proteins devoid of disulfide bonds appear capable of being cleaved, thereby preventing non-specific proteolysis of folded proteins (PubMed:8830688). Its proteolytic activity is essential for the survival of cells at elevated temperatures (PubMed:7557477). It can degrade IciA, Ada, casein, globin and PapA. DegP shares specificity with DegQ (PubMed:8830688). DegP is also involved in the biogenesis of partially folded outer-membrane proteins (OMP). |
| Product Overview | This product is a Mouse antibody against the degP. It can be used for degP antibody detection in ELISA, but Western Blot can be tested by the end of the user. |
| Alternative Names | Periplasmic serine endoprotease DegP; EC 3.4.21.107; Heat shock protein DegP; Protease Do; degP; htrA ptd; b0161 JW0157 |
| UniProt ID | P0C0V0 |
For Research Use Only | Not For Clinical Use.
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