Mouse Anti-ELANE Antibody (MO-AB-11955R)
Cat: MO-AB-11955R
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
MO-AB-11955R | Monoclonal | Cattle (Bos taurus), Dog, Rhesus (Macaca mulatta) | WB, ELISA | MO11955R | 100 µg | ||
CBMOAB-41649FYA | Monoclonal | Rhesus (Macaca mulatta) | WB, ELISA | MO41649FYA | 100 µg | ||
MOFY-0722-FY149 | Polyclonal | Dog | WB, IHC, ICC, IP | 100 µg |
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Cattle (Bos taurus), Dog, Rhesus (Macaca mulatta) |
Clone | MO11955R |
Specificity | This antibody binds to Cattle ELANE. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode structurally similar proteins. The encoded preproprotein is proteolytically processed to generate the active protease. Following activation, this protease hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix. The enzyme may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin. This protein also degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is present in a gene cluster on chromosome 19. (From NCBI) |
Product Overview | Mouse Anti-Cattle ELANE Antibody is a mouse antibody against ELANE. It can be used for ELANE detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | ELA2 protein; ELA2; ELANE |
UniProt ID | A6QPP7 |
Protein Refseq | The length of the protein is 267 amino acids long. The sequence is show below: MTQSCRRFSPALAPILLALLLGGPALASEIVGGRAARPHAWPFIASLQRRGGHFCGATLIARNFVLSAAHCLNGLNFRSVRVVLGAHNLRRQERTRQMFRVRRVFENGFDPLSLQNDVVVLQLNRMATLNANVQVARLPAQDQGVGEGVRCVAMGWGRLGTNRPPPQILQQLNVTVVTGLCRPTNVCTLVPRRRAGICFGDSGGPLVCNGLVHGIDSFIRGGCGSGVFPDSFASVAKFANWINSIIRRYSDDDGP. |
For Research Use Only | Not For Clinical Use.
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