Mouse Anti-Elob Antibody (CBMOAB-16224FYA)
Cat: CBMOAB-16224FYA
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
| Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
| CBMOAB-16224FYA | Monoclonal | Fruit fly (Drosophila melanogaster), Frog (Xenopus laevis), Rat (Rattus norvegicus) | WB, ELISA | MO16224FYA | 100 µg | ||
| MO-AB-03269H | Monoclonal | Frog (Xenopus laevis) | WB, ELISA | MO03269C | 100 µg | ||
| MO-AB-25631H | Monoclonal | Rat (Rattus norvegicus) | WB, ELISA | MO25631C | 100 µg |
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Fruit fly (Drosophila melanogaster), Frog (Xenopus laevis), Rat (Rattus norvegicus) |
| Clone | MO16224FYA |
| Specificity | This antibody binds to fruit fly Elob. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Nucleus; Other locations |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13. |
| Product Overview | Mouse Anti-D. melanogaster Elob Antibody is a mouse antibody against Elob. It can be used for Elob detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | RE59129p; EloB; Elongin-B |
| UniProt ID | Q8MYX5 |
| Protein Refseq | The length of the protein is 129 amino acids long. The sequence is show below: MQPQQSVSQSPLREQQTAANTSSKSTAAANRDKINPLTLSLACPTQTKCMKLKSKLMVGPDEGGGRSICLRFSTSQRGEEAKAAVSTAIAKYAFFVVNSKEQLIYYGSDTKLNFGMGLIIFGFNFTLTP. |
For Research Use Only | Not For Clinical Use.
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