Mouse Anti-F13A1 Antibody (CBMOAB-42141FYA)
Cat: CBMOAB-42141FYA
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
| Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
| CBMOAB-42141FYA | Monoclonal | Rhesus (Macaca mulatta), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Marmoset, Pig (Sus scrofa) | WB, ELISA | MO42141FYA | 100 µg | ||
| MO-AB-12215R | Monoclonal | Cattle (Bos taurus) | WB, ELISA | MO12215R | 100 µg | ||
| MO-AB-23593W | Monoclonal | Chimpanzee (Pan troglodytes) | WB, ELISA | MO23593W | 100 µg | ||
| MO-AB-25726R | Monoclonal | Pig (Sus scrofa) | WB, ELISA | MO25726R | 100 µg | ||
| MO-AB-55205W | Monoclonal | Marmoset | WB, ELISA | MO55205W | 100 µg |
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Rhesus (Macaca mulatta), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Marmoset, Pig (Sus scrofa) |
| Clone | MO42141FYA |
| Specificity | This antibody binds to Rhesus F13A1. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion. |
| Product Overview | Mouse Anti-Rhesus F13A1 Antibody is a mouse antibody against F13A1. It can be used for F13A1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Coagulation factor XIII A chain; F13A1 |
| UniProt ID | H9FKA1 |
| Protein Refseq | The length of the protein is 151 amino acids long. The sequence is show below: GILDTCLYVMDRAQMDLSGRGNPIKVSRVGSAMVNAKDDEGVLVGSWDNIYAYGVPPSAWTGSVDILLEYQSSENPVRYGQCWVFAGVFNTFLRCLGIPARIVTNYFSAHDNDANLQMDIFLEEDGNVNSKLTKDSVWNYHCWNEAWMTRP. |
For Research Use Only | Not For Clinical Use.
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