Mouse Anti-FAM111A Antibody (CBMOAB-42192FYA)
Cat: CBMOAB-42192FYA
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- Product List
- Specifications
- Application Information
- Target
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Rhesus (Macaca mulatta), Chimpanzee (Pan troglodytes) |
Clone | MO42192FYA |
Specificity | This antibody binds to Rhesus FAM111A. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Nucleus; Other locations |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | The protein encoded by this gene is cell-cycle regulated, and has nuclear localization. The C-terminal half of the protein shares homology with trypsin-like peptidases and it contains a PCNA-interacting peptide (PIP) box, that is necessary for its co-localization with proliferating cell nuclear antigen (PCNA). Reduced expression of this gene resulted in DNA replication defects, consistent with the demonstrated role for this gene in Simian Virus 40 (SV40) viral replication. Mutations in this gene have been associated with Kenny-Caffey syndrome (KCS) type 2 and the more severe osteocraniostenosis (OCS, also known as Gracile Bone Dysplasia), both characterized by short stature, hypoparathyroidism, bone development abnormalities, and hypocalcemia. Alternative splicing results in multiple transcript variants. (From NCBI) |
Product Overview | Mouse Anti-Rhesus FAM111A Antibody is a mouse antibody against FAM111A. It can be used for FAM111A detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | FAM111A |
UniProt ID | F6PVL0 |
Protein Refseq | The length of the protein is 611 amino acids long. The sequence is show below: MSCKKQRSQKHSVNEKCNMKIDHYFSPVSKKQQNNSSTSQIRMESRGGPRDVTNTQAQEFHSLKKNPEDQTMPKNRIILVTLDVNYRKNQNMKHELTHSENGSLYMALNTLQALRKEIETHQGQEMLVRGTEGIQGYINLGMPLSCFPESCHVVITFSQSKSKQKEDNHVFGRHDKASTECVKFYIHAVGIGKYKRRIVKCGKLHKKGCKLCVYAFKGETIKDALCKDGRFLSFLENDDWKLIENNDSILESTQPVDELEGKHFQVEVEKRMVPSAAASWNPESEKRNTCVLREQIVAQYPSLKRESEKIKENFKKKMKVKNGETLFKLHRVRFGKVTKNSSSIKVVKLLAHRSDSVGYLFWDSATTGCATCFVFKGLFILTCRHVIDYIVGDGIEPSKWAAIIGQCVRVTFGYEEPEGKETNYFFVEPWFEIHNEELDYAVLKLKENGQQVPMELYNGITPVPLSGLIHIIGHPYGDKKHIDACAVIPQGQRAKKCQEHVQSKEAESPEYVHMYTQSSFEEIVHNPDVITYDTEFFFGASGSPVFDSKGSLVAMHVAGFTYNYQNETRSIIEFGSTMESILLDIKQRYKPWYEEVFVSQQDVEMISGEDL. |
For Research Use Only | Not For Clinical Use.
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