Mouse Anti-FGFR1 Antibody (CBMOAB-42869FYA)


Cat: CBMOAB-42869FYA
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-42869FYA Monoclonal Rhesus (Macaca mulatta), Cat (Felis catus), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Elephant (Loxodonta africana), Ferret (Mustela Putorius Furo), Frog (Xenopus laevis), Guinea pig (Cavia porcellus), Horse (Equus caballus), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Chicken (Gallus gallus), Zebrafish (Danio rerio), Marmoset, Nile tilapia (Oreochromis niloticus), Pig (Sus scrofa), Rabbit (Oryctolagus cuniculus) WB, ELISA MO42869FYA 100 µg
MO-AB-00469L Monoclonal Elephant (Loxodonta africana) WB, ELISA MO00469L 100 µg
MO-AB-03591H Monoclonal Frog (Xenopus laevis) WB, ELISA MO03591C 100 µg
MO-AB-08086Y Monoclonal Rabbit (Oryctolagus cuniculus) WB, ELISA MO08086Y 100 µg
MO-AB-09361W Monoclonal Cat (Felis catus) WB, ELISA MO09361W 100 µg
MO-AB-12547R Monoclonal Cattle (Bos taurus) WB, ELISA MO12547R 100 µg
MO-AB-25832R Monoclonal Pig (Sus scrofa) WB, ELISA MO25832R 100 µg
MO-AB-26626W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO26626W 100 µg
MO-AB-30793W Monoclonal Dog (Canis lupus familiaris) WB, ELISA MO30793W 100 µg
MO-AB-33103H Monoclonal Nile tilapia (Oreochromis niloticus) WB, ELISA MO33103C 100 µg
MO-AB-34766W Monoclonal Ferret (Mustela Putorius Furo) WB, ELISA MO34766W 100 µg
MO-AB-41658W Monoclonal Guinea pig (Cavia porcellus) WB, ELISA MO41658W 100 µg
MO-AB-44752W Monoclonal Horse (Equus caballus) WB, ELISA MO44752W 100 µg
MO-AB-55433W Monoclonal Marmoset WB, ELISA MO55433W 100 µg
MO-DKB-03256W Polyclonal Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Chicken (Gallus gallus), Zebrafish (Danio rerio) WB, IHC, IHC-P 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRhesus (Macaca mulatta), Cat (Felis catus), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Elephant (Loxodonta africana), Ferret (Mustela Putorius Furo), Frog (Xenopus laevis), Guinea pig (Cavia porcellus), Horse (Equus caballus), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Chicken (Gallus gallus), Zebrafish (Danio rerio), Marmoset, Nile tilapia (Oreochromis niloticus), Pig (Sus scrofa), Rabbit (Oryctolagus cuniculus)
CloneMO42869FYA
SpecificityThis antibody binds to Rhesus FGFR1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationPlasma Membrane; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Product OverviewMouse Anti-Rhesus FGFR1 Antibody is a mouse antibody against FGFR1. It can be used for FGFR1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesFibroblast growth factor receptor; EC 2.7.10.1; FGFR1
UniProt IDF7A4U3
Protein RefseqThe length of the protein is 733 amino acids long.
The sequence is show below: MWSWKCLLFWAVLVTATLCTARPSPTLPEQDALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPSSGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCIVENEYGSINHTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKIGPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLEALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIVYKMKSGTKKSDFHSQMAVHKLAKSIPLRRQTRVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSHNPEEQLSSKDLVSCAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR.
For Research Use Only | Not For Clinical Use.
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