AibGenesis™ Mouse Anti-FHOD3 Antibody (CBMOAB-42900FYA)


Cat: CBMOAB-42900FYA

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Lot Number

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  • Specifications
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Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-42900FYA Monoclonal Rhesus (Macaca mulatta), Human (Homo sapiens), Mouse (Mus musculus), Cattle (Bos taurus), Dog (Canis lupus familiaris), Chicken (Gallus gallus), Horse (Equus caballus), Rat (Rattus norvegicus), Frog (Xenopus), Zebrafish (Danio rerio), Marmoset WB, ELISA MO42900FYA 100 µg
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MO-AB-55475W Monoclonal Marmoset WB, ELISA MO55475W 100 µg
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MO-DKB-03188W Polyclonal Human (Homo sapiens), Mouse (Mus musculus), Cattle (Bos taurus), Dog (Canis lupus familiaris), Chicken (Gallus gallus), Horse (Equus caballus), Rat (Rattus norvegicus), Frog (Xenopus), Zebrafish (Danio rerio) IHC, IHC-P 100 µg
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRhesus (Macaca mulatta), Human (Homo sapiens), Mouse (Mus musculus), Cattle (Bos taurus), Dog (Canis lupus familiaris), Chicken (Gallus gallus), Horse (Equus caballus), Rat (Rattus norvegicus), Frog (Xenopus), Zebrafish (Danio rerio), Marmoset
CloneMO42900FYA
SpecificityThis antibody binds to Rhesus FHOD3.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene is a member of the diaphanous-related formins (DRF), and contains multiple domains, including GBD (GTPase-binding domain), DID (diaphanous inhibitory domain), FH1 (formin homology 1), FH2 (formin homology 2), and DAD (diaphanous auto-regulatory domain) domains. This protein is thought to play a role in actin filament polymerization in cardiomyocytes. Mutations in this gene have been associated with dilated cardiomyopathy (DCM), characterized by dilation of the ventricular chamber, leading to impairment of systolic pump function and subsequent heart failure. Increased levels of the protein encoded by this gene have been observed in individuals with hypertrophic cardiomyopathy (HCM). Alternative splicing results in multiple transcript variants encoding different isoforms. A muscle-specific isoform has been shown to possess a casein kinase 2 (CK2) phosphorylation site at the C-terminal end of the FH2 domain. Phosphorylation of this site alters its interaction with sequestosome 1 (SQSTM1), and targets this isoform to myofibrils, while other isoforms form cytoplasmic aggregates. (From NCBI)
Product OverviewMouse Anti-Rhesus FHOD3 Antibody is a mouse antibody against FHOD3. It can be used for FHOD3 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesFHOD3
UniProt IDF7F8V9
Protein RefseqThe length of the protein is 654 amino acids long.
The sequence is show below: MATLACRVQFLDDTDPFNSTNFPEPSRPPLFTFREDLALGTQLVGVHRLLRAPHKLDDCTLQLSHNGAYLDLEATLAEQRDELEGFQDDAGRGKKHSIILRTQLSVRVHACIEKLYNSSGRDLRRALFSLKQIFQDDKDLVHEFVVAEGLTCLIKVGAEADQNYQNYILRALGQIMLYVDGMNGVINHNETIQWLYTLIGSKFRLVVKTALKLLLVFVEYSESNAPLLIQAVTAVDTKRGVKPWSNIMEILEEKDGVDTELLVYAMTLVNKTLSGLPDQDTFYDVVDCLEELGIAAVSQRHLNKKGTDLDLVEQLNIYEVALRHEDGDETAEPPPSGCRDRRRASVCSSGGGEHRGLDRRRSRRHSVQSIKSTLSAPTSPCSQSAPSFKPSQVRDLREKYSNFGNNSHHSSRPSSGSSVPTTPTSSISPPQEARLERSSPSGLLTSSFRQHQESLAAERERRRQEREERLQRIEREERNKFRYKYLEQLAAEEHEKELRSRSVSRGRADLSLDLTSPAAPACPAPLSHSPSSLDSQEALTVSPSSPGTPHHPQASAGDPEPESEAEPEPEAGAGQVADEAGQDIASAHEGAETEVEQALEQEPEERASLSEKERQNEGVNERDNCSASSVSSSSSTLEREEKEDKLSGDRTTGK.
For Research Use Only | Not For Clinical Use.
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