Mouse Anti-Frog rbl1 Antibody (MO-AB-06960H)
Cat: MO-AB-06960H
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Frog (Xenopus laevis) |
| Clone | MO06960C |
| Specificity | This antibody binds to Frog rbl1. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Nucleus; Other locations |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene. |
| Product Overview | This product is a mouse antibody against rbl1. It can be used for rbl1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | MGC84607 protein; rbl1; MGC84607 |
| UniProt ID | Q6NRA7 |
| Protein Refseq | The length of the protein is 998 amino acids long. The sequence is show below: MEHLQSGGRSQALASMCLVCSMSKKRHTNSWKRNHGGNGVSLTRILRSAKLSLIQFFNKMKKWIDMSNLPQEFRERVERLERNFEVATVIFKKFEPIFREIFQNPHDEQPRLPRSRKQSILFCRRLQCSVKDLFSFCWTLFVYSKGNFCLIGDDLVNSYHLLLCCLDLIYAHVLQCPNKEDLLNPSFTAKLALDSSSEDTPCIIGALCELYDGISVEAKGIKEHYFKPYIAKLHDKKILKGACLLDVSCFTDNNKSLNKEYEEYVLTKGDFDERVFLGVDADEEIGSPRKFVEFPIGNCTPRKQMECNLQQHFEKKRSFAPSTPLTGRGYLKEEQTVITPVSSATQCVSRLQSMVAGLRNAPSEQLIEVFKSCVRNPIENVLNIVRDIGLRFVDHYTQSTEDQPGSHIDFAVNRWKLAEILYFKVLETIVVQESRRLHGKDLTALLEQDIFHQSLIACCLEIVLFAYSSPKTFPWTIEVLKLSAFYFYKVIEVFIRSEDGLSRDMVKHLNTIEEQILESRAWTSDSVLWVHLDAVDDVPTCEEVIIPSNFETGNEALVGHLPMIPASPIVHPRVKDLGGSYRRDCQPLSPISVHDRYSSPAAGSAKRRLFGDDCPREPAADKITTPDITRIRIAISPSPVKTVYPIGHAVAIPVQGVALETGKSLSVTMKTSPSQSENSVPVPLTAQALISPLTKHQLGRNLETCPTSARKPKKTGSLALFFRKMYHLASVRLRDLCLKLDVSNDLRRKIWTLFVYSLVHCTDLMKDRHLDQLLLCAVYIMAKISKEERLFHDIMKCYRNQPQANSHVYRSVLLKRLPQASEDETSTSQDVEMTASNSNDSHPTPSGFTGSPCGQAERGDLITFYNNVYVERVRLFALKFSSSTQDHLVDAPPLSPFPSIKQQAISPRRVSQQHSIYVSPHKNSGNLTPHTALLYKFNGSPSKSLQDINSMLKQEQRSRKRIIAIDSDTESPAKRLCQENDDALLKRLQDVVSERANH. |
See other products for " RBL1 "
| CBMOAB-39867FYC | Mouse Anti-Arabidopsis RBL1 Antibody (CBMOAB-39867FYC) |
| MO-AB-17098W | Mouse Anti-Chimpanzee RBL1 Antibody (MO-AB-17098W) |
| MO-AB-05566W | Mouse Anti-Rhesus RBL1 Antibody (MO-AB-05566W) |
| CBMOAB-95417FYA | Mouse Anti-Zebrafish rbl1 Antibody (CBMOAB-95417FYA) |
For Research Use Only | Not For Clinical Use.
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