AibGenesis™ Mouse Anti-Fz2 Antibody (CBMOAB-17108FYA)
Cat: CBMOAB-17108FYA
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
| Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
| CBMOAB-17108FYA | Monoclonal | Fruit fly (Drosophila melanogaster), Chicken (Gallus gallus), D. melanogaster (Drosophila melanogaster) | WB, ELISA | MO17108FYA | 100 µg | ||
| MO-AB-01963Y | Monoclonal | Chicken (Gallus gallus) | WB, ELISA | MO01963Y | 100 µg | ||
| MO-NAB-00604W | Monoclonal | D. melanogaster (Drosophila melanogaster) | IHC, WB | NW0526 | 100 µg | ||
| MO-NAB-00616W | Monoclonal | D. melanogaster (Drosophila melanogaster) | IF, WB | NW0538 | 100 µg |
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Fruit fly (Drosophila melanogaster), Chicken (Gallus gallus), D. melanogaster (Drosophila melanogaster) |
| Clone | MO17108FYA |
| Specificity | This antibody binds to fruit fly Fz2. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. Required to coordinate the cytoskeletons of epidermal cells to produce a parallel array of cuticular hairs and bristles. (From uniprot, under CC BY 4.0) |
| Product Overview | Mouse Anti-D. melanogaster Fz2 Antibody is a mouse antibody against Fz2. It can be used for Fz2 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Frizzled 2, isoform F; fz2 |
| UniProt ID | M9PFW3 |
| Protein Refseq | The length of the protein is 806 amino acids long. The sequence is show below: MRHNRLKVLILGLVLLLTSCRADGPLHSADHGMGGMGMGGHGLDASPAPGYGVPVIPKDPNLRCEEITIPMCRGIGYNMTSFPNEMNHETQDEAGLEVHQFWPLVEIKCSPDLKFFLCSMYTPICLEDYHKPLPVCRSVCERARSGCAPIMQQYSFEWPERMACEHLPLHGDPDNLCMEQPSYTEAGSGGSSGGSGGSGSGSGSGGKRKQGGSGSGGSGAGGSSGSTSTKPCRGRNSKNCQNPQGEKASGKECSCSCRSPLIFLGKEQLLQQQSQMPMMHHPHHWYMNLTVQRIAGVPNCGIPCKGPFFSNDEKDFAGLWIALWSGLCFCSTLMTLTTFIIDTERFKYPERPIVFLSACYFMVAVGYLSRNFLQNEEIACDGLLLRESSTGPHSCTLVFLLTYFFGMASSIWWVILSFTWFLAAGLKWGNEAITKHSQYFHLAAWLIPTVQSVAVLLLSAVDGDPILGICYVGNLNPDHLKTFVLAPLFVYLVIGTTFLMAGFVSLFRIRSVIKQQGGVGAGVKADKLEKLMIRIGIFSVLYTVPATIVIGCYLYEAAYFEDWIKALACPCAQVKGPGKKPLYSVLMLKYFMALAVGITSGVWIWSGKTLESWRRFWRRLLGAPDRTGANQALIKQRPPIPHPYAGSGMGMPVGSAAGSLLATPYTQAGGASVASTSHHHLHHHVLKQPAASHVXHGESGGASTMGGGGGGGSTLGGGTLGHGTAMSSSTVGMGPLPGTLMHGASGGGVGGGNPGNVYGNGNNGVGGQNTAPGSVIDSRAVSVVVTLPGGPGAQHPGQALSDYGPI. |
For Research Use Only | Not For Clinical Use.
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