Mouse Anti-GPX1 Antibody (CBMOAB-34188FYC)


Cat: CBMOAB-34188FYC
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-34188FYC Monoclonal A. thaliana (Arabidopsis thaliana), C. elegans (Caenorhabditis elegans), Cat (Felis catus), Cattle (Bos taurus), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Elephant (Loxodonta africana), Ferret (Mustela Putorius Furo), Frog (Xenopus laevis), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Primat, Rhesus (Macaca mulatta), Medaka (Oryzias latipes), Rabbit (Oryctolagus cuniculus), Yeast WB, ELISA MO34188FC 100 µg
CBMOAB-01572CR Monoclonal Yeast WB, ELISA MO01572CR 100 µg
CBMOAB-04654HCB Monoclonal C. elegans (Caenorhabditis elegans) WB, ELISA MO04654HB 100 µg
MO-AB-08785W Monoclonal Cat (Felis catus) WB, ELISA MO08785W 100 µg
MO-AB-14469W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO14469W 100 µg
MO-AB-31013W Monoclonal Dog (Canis lupus familiaris) WB, ELISA MO31013W 100 µg
MO-AB-34857W Monoclonal Ferret (Mustela Putorius Furo) WB, ELISA MO34857W 100 µg
MO-AB-13331R Monoclonal Cattle (Bos taurus) WB, ELISA MO13331R 100 µg
MO-AB-00625R Monoclonal Medaka (Oryzias latipes) WB, ELISA MO00625R 100 µg
MO-AB-04043H Monoclonal Frog (Xenopus laevis) WB, ELISA MO04043C 100 µg
MO-AB-26099H Monoclonal Rat (Rattus norvegicus) WB, ELISA MO26099C 100 µg
MO-AB-00579L Monoclonal Elephant (Loxodonta africana) WB, ELISA MO00579L 100 µg
MO-AB-02214Y Monoclonal Chicken (Gallus gallus) WB, ELISA MO02214Y 100 µg
MO-AB-08258Y Monoclonal Rabbit (Oryctolagus cuniculus) WB, ELISA MO08258Y 100 µg
MO-DKB-00593W Polyclonal Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Primat, Rhesus (Macaca mulatta) WB, IB, IF, IHC, IHC-P 100 µg
MO-DKB-01996W Polyclonal A. thaliana (Arabidopsis thaliana) WB 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityA. thaliana (Arabidopsis thaliana), C. elegans (Caenorhabditis elegans), Cat (Felis catus), Cattle (Bos taurus), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Elephant (Loxodonta africana), Ferret (Mustela Putorius Furo), Frog (Xenopus laevis), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Primat, Rhesus (Macaca mulatta), Medaka (Oryzias latipes), Rabbit (Oryctolagus cuniculus), Yeast
CloneMO34188FC
SpecificityThis antibody binds to Arabidopsis GPX1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationChloroplast; Vacuole

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Other studies indicate that H2O2 is also essential for growth-factor mediated signal transduction, mitochondrial function, and maintenance of thiol redox-balance; therefore, by limiting H2O2 accumulation, glutathione peroxidases are also involved in modulating these processes. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is the most abundant, is ubiquitously expressed and localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. It is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. This gene contains an in-frame GCG trinucleotide repeat in the coding region, and three alleles with 4, 5 or 6 repeats have been found in the human population. The allele with 4 GCG repeats has been significantly associated with breast cancer risk in premenopausal women. Alternatively spliced transcript variants have been found for this gene. Pseudogenes of this locus have been identified on chromosomes X and 21.
Product OverviewMouse Anti-Arabidopsis GPX1 Antibody is a mouse antibody against GPX1. It can be used for GPX1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesGlutathione Peroxidase 1; Cellular Glutathione Peroxidase; EC 1.11.1.9; GSHPx-1; EC 1.11.1; GSHPX1; GPx-1; GPXD
UniProt IDP52032
Protein RefseqThe length of the protein is 236 amino acids long. The sequence is show below: MVSMTTSSSSYGTFSTVVNSSRPNSSATFLVPSLKFSTGISNFANLSNGFSLKSPINPGFLFKSRPFTVQARAAAEKTVHDFTVKDIDGKDVALNKFKGKVMLIVNVASRCGLTSSNYSELSHLYEKYKTQGFEILAFPCNQFGFQEPGSNSEIKQFACTRFKAEFPIFDKVDVNGPSTAPIYEFLKSNAGGFLGGLIKWNFEKFLIDKKGKVVERYPPTTSPFQIEKDIQKLLAA.
For Research Use Only | Not For Clinical Use.
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