Name: AibGenesis™ Mouse Anti-GRAMD1A Antibody (CBMOAB-44079FYA)
SKU: CBMOAB-44079FYA
Rating: 5 (1 reviews)

Sub Cat	Clonality	Species Reactivity	Application	Clone	Conjugate	Size
CBMOAB-44079FYA	Monoclonal	Rhesus (Macaca mulatta), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Marmoset, Zebrafish (Danio rerio)	WB, ELISA	MO44079FYA		100 µg	Inquiry
Protein Refseq: The length of the protein is 713 amino acids long. The sequence is show below: MFDTTPHSGRSTPSSSPSLRKRLQLLPPSRPPPEPEPGTMVEKGSDSSSEKGGVPGTPSTQSLGSRNFIRNSKMLSPTYKQRNEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLLIFRLWQNALLEKVGLGEAWVGMGSSQGVHGARDPRTCQAVGAQLFSMGTRPGQVRKLMARASETSLAGAERGPHWPQATRSSATSPRVAKAASGISLQAEEDKEEQVDSQPDASSSQTVTPVAEPPSTEPTQPDGPTTLGPLDLLPSEELLTDTSNSSSSTGEEGDFSQCRPPASGPLLIPHLLRERPPRRLSLLRPVGKGLGCGLLMLLLPPLDVTLSPWSGDSKCHQRRVLTYTIPISNPLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYFYTAHRYCILGVARNKARLRVSSEIRYRKQPWSLVKSLIEKNSWSGIEDYFHHLERELTKAEKLSLEEGGKDARSLLSGLRRRKRPLSWRAHGDGPQHPDPDPCARAGMHTSGSLSSRFSEPSVDQGPGAGIPNALVLISIVLIILIALNVLLFYRLWSLERTAHTFESWHSLALAKGKFPQTATEWAEILALQKQFHSVEVHKWRQILRASVELLDEMKFSLEKLHQGITVSDPPFDTQPRPEDSFS.
CBMOAB-78589FYA	Monoclonal	Zebrafish (Danio rerio)	WB, ELISA	MO78589FYA		100 µg	Inquiry
Protein Refseq: The length of the protein is 896 amino acids long. The sequence is show below: MYEGLLVMAMTTPPEILIAEPISIPILNILPPSSDTESWSRSPSPRAHRYRSRSREKRKAKAQQEDKSGAKHCDKRKGELERSPSHASASSSMVCNVDDEEQGNPCVLLLPPSRSWSRSSSLSRRSRWSIRSLLNKDSDCDSSSTASNSPRSTPGSSPSLRRRVLGGRASEGETAGEKSGGGSDSPLPPTPSSSTSSYPLAARHFTRNAKVLSPTYKQRNEDFRKLFKKLPDTERLIVDYSCALQKDILLQGRLYLSENWLCFYSNIFRWETTITILLKDVTNLTKEKTAKLIPNAIQISTENEKHFFTSFGARDRSYMMIFRLWQNALMDKTLSPKELWHIVHQCYGTELGLTSEDDDYVSPTAEHMNGLLPGEEPVSVTDLLDLGSVPVAPASSSPPSSASVLPCASGSSPPSSSSSSQPVEVPSIRASIDPEPSPPSSQSSLPPVTNTGAVPASVILKEGGDSQSESANHSLQSPPSIPHNLGNLSSLDMTNDEDLPTDPSNSSDTQEESEVESFCADLNGRLHINTVVRMGVDKLHDLLFSDTHFIQHLFSQRHFTDLSVHEWQQDSSSGSSSRVLSYTIAINNPLGPKTAPVVETQTLHKSSSRSECYVVDSEVITSGIPYQDYFYTVHRYCLTSVNKHKSRLRVSSDICYRKQPWSLVKALIEKNTWSGIEEYYRHLEMEVCKLETLLQTEVTVVSAGEMPSPDSTKTPPGLRRRKRTCPRRAGERDRDREAAGGGERGDRITDERDRREAGGQYMKLGERWRAGGGSNNNSISTILLIVSFILVVLVALNMMLFYKLWALERAAHTLETWHSYSLTDSPLPQSAGEWAQVLQLQRQFHQAQMNKWQQILQSSVTLLDQMKQSLEKLHRGMIPPEGQQESDPEPDTLADQ.
MO-AB-03740W	Monoclonal	Rhesus (Macaca mulatta)	WB, ELISA	MO03740W		100 µg	Inquiry
Protein Refseq: The length of the protein is 807 amino acids long. The sequence is show below: MDEVLPLMPWETLLAQGSPQGSPALPAGQRKQQPQGDRAQGLASESWKLLEVPIIHITPSSDGESPACTPTLQRRQQLRTPDPQSPSQDSTTPHSGRSTPSSSPSLRKRLQLLPPSRPPPEPEPGTMVEKGSDSSSEKGGVPGTPSTQSLGSRNFIRNSKKMQSWYSMLSPTYKQRNEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLLIFRLWQNALLEKTLSPRELWHLVHQCYGSELGLTSEDEDYVCPLQLNGLGAPKEVGDVIALSDITSSGAADRSQEPSPVGSRRGRVTPNLSRASSDADHGAEEDKEEQVDSQPDASSSQTVTPVAEPPSTEPTQPDGPTTLGPLDLLPSEELLTDTSNSSSSTGEEADLAALLPDLSGRLLINSVFHVGAERLQQMLFSDSPFLQGFLQQCKFTDVTLSPWSGDSKCHQRRVLTYTIPISNPLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYFYTAHRYCILGVARNKARLRVSSEIRYRKQPWSLVKSLIEKNSWSGIEDYFHHLERELTKAEKLSLEEGGKDARSLLSGLRRRKRPLSWRAHGDGPQHPDPDPCARAGMHTSGSLSSRFSEPSVDQGPGAGIPNALVLISIVLIILIALNVLLFYRLWSLERTAHTFESWHSLALAKGKFPQTATEWAEILALQKQFHSVEVHKWRQILRASVELLDEMKFSLEKLHQGITVSDPPFDTQPRPEDSFS.
MO-AB-13339R	Monoclonal	Cattle (Bos taurus)	WB, ELISA	MO13339R		100 µg	Inquiry
Protein Refseq: The length of the protein is 711 amino acids long. The sequence is show below: RSTPSSSPSLRKRLQLLPTSRPPPEPEPGTMVEKGSDSSSEKGGVPGTPSTQSLGSRNFIRNSKKMQSWYSMLSPTYKQRNEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTENEKHFFTSFGARDRCFLLIFRLWQNALLEKTLSPRELWHLVHQCYGSELGLTSEDEDYVCPLQLNGLGSPKDVGDVIALSDITPSGAADHSQ.
MO-AB-17096W	Monoclonal	Chimpanzee (Pan troglodytes)	WB, ELISA	MO17096W		100 µg	Inquiry
Protein Refseq: The length of the protein is 720 amino acids long. The sequence is show below: MFDTTPHSGRSTPSSSPSLRKRLQLLPPSRPPPDPEPGTMVEKGSDSSSEKGGVPGTPSTQSLGSRNFIRNSKKMQSWYSMLSPTYKQRNEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLLIFRLWQNALLEKTLSPRELWHLVHQCYGSELGLTSEDEDYVSPLQLNGLGTPKEVGDVIALSDITSSGAADRSQEPSPVGSRRGRVTPNLSRASSDADHGAEEDKEEQVDSQPDASSSQTVTPVAEPPSTEPTQPDGPTTLGPLDLLPSEELLTDTSNSSSSTGEEADLAALLPDLSGRLLINSVFHVGAERLQQMLFSDSPFLQGFLQQCKFTDVTLSPWSGDSKCHQRRVLTYTIPISNPLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYFYTAHRYCILGLARNKARLRVSSEIRYRKQPWSLVKSLIEKNSWSGIEDYFHHLERELAKAEKLSLEEGGKDARGLLSGLRRRKRPLSWRAHGDGPQHPDPDPCARAGMHTSGSLSSRFSEPSVDQGPGAGIPSALVLISIVLIILIALNVLLFYRLWSLERTAHTFESWHSLALAKGKFPQTATEWAEILALQKQFHSVEVHKWRQILRASVELLDEMKFSLEKLHQGITVSDPPFDTQPRPDDSFS.
MO-AB-56335W	Monoclonal	Marmoset	WB, ELISA	MO56335W		100 µg	Inquiry
Protein Refseq: The length of the protein is 727 amino acids long. The sequence is show below: MFDTTPHSGRSTPSSSPSLRKRLQLLPPSRPPPEPEPGTMVEKGSDSSSEKGGVPGTPSTQSLGSRNFIRNSKKMQSWYSMLSPTYKQRNEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLLIFRLWQNALLEKTLSPRELWHLVHQCYGSELGLTSEDEDYVCPLQLNGLGTPKEVGDVIALSDITSSGAADRSQEASPVGSRRGRVTPNLSRASSDADHGAEEDKEEQVDSQPDASSSQTVTPVAEPPSTEPTPPDGPTTLGPLDLLPSEELLTDTSNSSSSTGEEGEAADLAALLPDLSGRLLINSVFHVGAERLQQMLFSDSPFLQGFLQQCKFTDVTLSPWSGDSKCHQRRVLTYTIPISNPLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYFYTAHRYCILGLARNKARLRVSSEIRYRKQPWSLVKSLIEKNSWSGIEDYFHHLERELAKAEKLSLEEGGKDARGLLSGLRRRKRPLSWRAHGDGPQHPDPDPCARAGMHTSGSLSSRFSEPSVDQGPGAGIPSALVLISIVICVSLIILIALNVLLFYRLWSLERTAHTFESWHSLALAKGKIPQTATEWAEILALQKQFHSVEVHKWRQILRASVELLDEMKFSLEKLHQGITVSDPPFDAQPRPDDSFS.

Specifications

Host species	Mouse (Mus musculus)
Species Reactivity	Rhesus (Macaca mulatta), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Marmoset, Zebrafish (Danio rerio)
Clone	MO44079FYA
Specificity	This antibody binds to Rhesus GRAMD1A.
Format	Liquid or Lyophilized
Storage	Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use
Purity	> 90% was determined by SDS-PAGE
Purification	Purified with Protein A or G affinity chromatography

Application Information

Application	WB, ELISA
Application Notes	ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

Introduction	Cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER). Contains unique domains for binding cholesterol and the PM, thereby serving as a molecular bridge for the transfer of cholesterol from the PM to the ER. Plays a crucial role in cholesterol homeostasis and has the unique ability to localize to the PM based on the level of membrane cholesterol. In lipid-poor conditions localizes to the ER membrane and in response to excess cholesterol in the PM is recruited to the endoplasmic reticulum-plasma membrane contact sites (EPCS) which is mediated by the GRAM domain. At the EPCS, the sterol-binding VASt/ASTER domain binds to the cholesterol in the PM and facilitates its transfer from the PM to ER. May play a role in tumor progression. Plays a role in autophagy regulation and is required for biogenesis of the autophagosome (PubMed:31222192). This function in autophagy requires its cholesterol-transfer activity. (From uniprot, under CC BY 4.0)
Product Overview	Mouse Anti-Rhesus GRAMD1A Antibody is a mouse antibody against GRAMD1A. It can be used for GRAMD1A detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative Names	GRAMD1A
UniProt ID	F7G8T1
Protein Refseq	The length of the protein is 713 amino acids long. The sequence is show below: MFDTTPHSGRSTPSSSPSLRKRLQLLPPSRPPPEPEPGTMVEKGSDSSSEKGGVPGTPSTQSLGSRNFIRNSKMLSPTYKQRNEDFRKLFSKLPEAERLIVDYSCALQREILLQGRLYLSENWICFYSNIFRWETTISIQLKEVTCLKKEKTAKLIPNAIQICTESEKHFFTSFGARDRCFLLIFRLWQNALLEKVGLGEAWVGMGSSQGVHGARDPRTCQAVGAQLFSMGTRPGQVRKLMARASETSLAGAERGPHWPQATRSSATSPRVAKAASGISLQAEEDKEEQVDSQPDASSSQTVTPVAEPPSTEPTQPDGPTTLGPLDLLPSEELLTDTSNSSSSTGEEGDFSQCRPPASGPLLIPHLLRERPPRRLSLLRPVGKGLGCGLLMLLLPPLDVTLSPWSGDSKCHQRRVLTYTIPISNPLGPKSASVVETQTLFRRGPQAGGCVVDSEVLTQGIPYQDYFYTAHRYCILGVARNKARLRVSSEIRYRKQPWSLVKSLIEKNSWSGIEDYFHHLERELTKAEKLSLEEGGKDARSLLSGLRRRKRPLSWRAHGDGPQHPDPDPCARAGMHTSGSLSSRFSEPSVDQGPGAGIPNALVLISIVLIILIALNVLLFYRLWSLERTAHTFESWHSLALAKGKFPQTATEWAEILALQKQFHSVEVHKWRQILRASVELLDEMKFSLEKLHQGITVSDPPFDTQPRPEDSFS.