Mouse Anti-GSTM4 Antibody (CBMOAB-44209FYA)


Cat: CBMOAB-44209FYA
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Lot Number

  • Product List
  • Specifications
  • Application Information
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Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-44209FYA Monoclonal Rhesus (Macaca mulatta), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Marmoset, Rat (Rattus norvegicus) WB, ELISA MO44209FYA 100 µg
CBMOAB-60164FYC Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO60164FYC 100 µg
MO-AB-13410R Monoclonal Cattle (Bos taurus) WB, ELISA MO13410R 100 µg
MO-AB-24244W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO24244W 100 µg
MO-AB-26156H Monoclonal Rat (Rattus norvegicus) WB, ELISA MO26156C 100 µg
MO-AB-56464W Monoclonal Marmoset WB, ELISA MO56464W 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRhesus (Macaca mulatta), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Marmoset, Rat (Rattus norvegicus)
CloneMO44209FYA
SpecificityThis antibody binds to Rhesus GSTM4.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionCytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. Multiple transcript variants, each encoding a distinct protein isoform, have been identified.
Product OverviewMouse Anti-Rhesus GSTM4 Antibody is a mouse antibody against GSTM4. It can be used for GSTM4 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesGlutathione S-transferase Mu 5; GSTM4
UniProt IDH9EYA0
Protein RefseqThe length of the protein is 205 amino acids long.
The sequence is show below: MSMTLGYWDIRGLAHAIRLLLEYTDSNYEEKKYRMGHAPDYDRSQWLNEKFKLGLDFPNLPYLIDGTHKITQSNAILRYIARKHNLCGETEEEKILVDILENQLMDSRMEMVRLCFDPNFEKLKPKYLEELPEKLKLYSQFLGKRPWFTGDKITFVDFLAYDVLDMRRIVEPGCLDAFPNLKDFISRFEGLKKISAYMKSSRFLP.
For Research Use Only | Not For Clinical Use.
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