Anti-H2B Antibody (Cat MO-MMB-0694), Rabbit IgG

Cat: MO-MMB-0694
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  • Product Details


Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityBudding Yeast, Fission Yeast
ImmunogenRecombinant yeast histone H2B.
Buffer30% Glycerol
Regulatory StatusFor Research Use Only
ShippingGel Pack
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Application Information

ApplicationChIP, WB
Application NotesWB: 1:1000-1:5000
The optimal dilution should be determined by the end user.


IntroductionHistone H2B is one of the core components of nucleosomes. The nucleosome is the smallest subunit of chromatin and consists of 147 DNA base pairs wrapped around the core histone octamer (histone H2A, histone H2B, histone H3, and histone H4). Histone H1 is a linker histone that exists at the interface between the nucleosome core and the DNA entry/exit point; it is responsible for building higher-order chromatin structures. Chromatin undergoes a variety of chemical modifications, including post-translational modifications of histones and methylation of cytosine residues in DNA. The reported histone modifications include acetylation, methylation, phosphorylation, ubiquitination, glycosylation, ADP-ribosylation, carbonylation and SUMOylation; they play a major role in regulating gene expression.
Alternative NamesH2B; Histone H2B


For Research Use Only | Not For Clinical Use.

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