Mouse Anti-His2Av Antibody (CBMOAB-20540FYA)
Cat: CBMOAB-20540FYA
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
| Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
| CBMOAB-20540FYA | Monoclonal | Fruit fly (Drosophila melanogaster), D. melanogaster (Drosophila melanogaster) | WB, ELISA | MO20540FYA | 100 µg | ||
| MO-NAB-00869W | Monoclonal | D. melanogaster (Drosophila melanogaster) | ELISA, IF, WB | NW0791 | 100 µg | ||
| MO-DKB-00513W | Polyclonal | Fruit fly (Drosophila melanogaster) | WB, ELISA, IF, IHC | 100 µg | |||
| MO-DKB-03707W | Polyclonal | D. melanogaster (Drosophila melanogaster) | ELISA, WB, IHC | 100 µg |
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Fruit fly (Drosophila melanogaster), D. melanogaster (Drosophila melanogaster) |
| Clone | MO20540FYA |
| Specificity | This antibody binds to fruit fly His2Av. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Nucleus; Other locations |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Acts as a Polycomb group (PcG) protein required to maintain the transcriptionally repressive state of homeotic genes of the animal throughout development. Required for histone H3 'Lys-9' methylation and histone H4 'Lys-12' acetylation, two modifications that are essential for heterochromatin formation. Also involved in DNA double strand break (DSB) repair. Essential for early development. (From uniprot, under CC BY 4.0) |
| Product Overview | Mouse Anti-D. melanogaster His2Av Antibody is a mouse antibody against His2Av. It can be used for His2Av detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Histone H2A.v; H2A.F/Z; H2A.Z; His2Av; H2AvD His2AvD |
| UniProt ID | P08985 |
| Protein Refseq | The length of the protein is 141 amino acids long. The sequence is show below: MAGGKAGKDSGKAKAKAVSRSARAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKEETVQDPQRKGNVILSQAY. |
For Research Use Only | Not For Clinical Use.
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