Mouse Anti-IL-17A Antibody (MOFAB-324W)


Cat: MOFAB-324W
Certificate of Analysis Lookup
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
MOFAB-324W Monoclonal Cow, Dog, Horse, Human, Non-human primate, Pig, Sheep, Goat, Medaka (Oryzias latipes) FC WMT504 100 µg
MO-AB-00749R Monoclonal Medaka (Oryzias latipes) WB, ELISA MO00749R 100 µg
MO-AB-00750R Monoclonal Medaka (Oryzias latipes) WB, ELISA MO00750R 100 µg
MO-AB-00751R Monoclonal Medaka (Oryzias latipes) WB, ELISA MO00751R 100 µg
MOFAB-323W Monoclonal Cow, Dog, Horse, Human, Non-human primate, Pig, Sheep ELISA, ELISpot, FC WMT504 100 µg
MOFAB-340W Monoclonal Cow, Goat, Sheep ELISA, ELISpot WMT51B8 100 µg

Specifications

Host speciesMouse
Species ReactivityCow, Dog, Horse, Human, Non-human primate, Pig, Sheep, Goat, Medaka (Oryzias latipes)
CloneWMT504
SpecificityNative and recombinant IL-17A.
FormatLiquid or Lyophilized
BufferPBS, 0.2% BSA
Regulatory StatusFor Research Use Only
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use

Application Information

ApplicationFC
Application NotesThe optimal dilution should be determined by the end user.

Target

IntroductionIL-17A (IL-17A, IL17A) is a potent pro-inflammatory cytokine produced by activated Th17 (T helper 17) cells and certain cells belonging to the innate immune system. In mice, IL-17 has also been shown to be produced by activated CD8+ T cells and γδ T cells. Th17 cells play an important role in autoimmune diseases and resistance to bacteria and fungi. IL-17A acts on a wide range of cell types to induce the expression of cytokines, chemokines and metalloproteinases. Therefore, secretion of IL-17A promotes the inflammatory response, which leads to the recruitment of neutrophils, enhancement of antibody production, and activation of T cells. Increased IL-17A expression is seen in autoimmune diseases such as multiple sclerosis and rheumatoid arthritis. It has also been linked to asthma, psoriasis, cancer and transplant rejection.
Product OverviewThe IL-17A antibody is used as Veterinary research antibodies.
Alternative NamesInterleukin-17A/F-1; IL-17A/F-1; human IL-17A
See other products for " IL-17A "
For Research Use Only | Not For Clinical Use.
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