Rat Anti-IL6 Antibody (MOFY-0522-FY45)


Cat: MOFY-0522-FY45
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Specifications

Host speciesRat
Species ReactivityHuman, Rhesus, Cynomolgus
ImmunogenCOS-expressed human IL-6
FormatLiquid or Lyophilized
BufferPBS, pH 7.4
Regulatory StatusFor Research Use Only. Not For Clinical Use.
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use

Application Information

ApplicationFC, IP, ELISA, ELISpot, Neut
Application NotesThe optimal dilution should be determined by the end user.

Target

IntroductionInterleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory muscle factor. In humans, it is encoded by the IL6 gene.

In addition, osteoblasts secrete IL-6 to stimulate osteoclast formation. Many vascular smooth muscle cells also produce IL-6 as a proinflammatory cytokine. The role of IL-6 as an anti-inflammatory actin is mediated by its inhibitory effect on TNF-α and IL-1 and the activation of IL-1ra and IL-10.

Early evidence suggests that in the context of a broader coronavirus pandemic, IL-6 can be used as an inflammatory marker of severe COVID-19 infection with a poor prognosis.
Alternative NamesIL6; BSF2; HGF; HSF; IFNB2; IL-6; BSF-2; CDF; IFN-beta-2; interleukin 6
Gene ID705819(Rhesus)
UniProt IDP51494(Rhesus)
For Research Use Only | Not For Clinical Use.
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