Mouse Anti-Incenp Antibody (CBMOAB-21034FYA)


Cat: CBMOAB-21034FYA
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-21034FYA Monoclonal Fruit fly (Drosophila melanogaster), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Medaka (Oryzias latipes), Rhesus (Macaca mulatta), Silkworm (Bombyx mori) WB, ELISA MO21034FYA 100 µg
CBMOAB-45397FYA Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO45397FYA 100 µg
MO-AB-00762R Monoclonal Medaka (Oryzias latipes) WB, ELISA MO00762R 100 µg
MO-AB-02565Y Monoclonal Chicken (Gallus gallus) WB, ELISA MO02565Y 100 µg
MO-AB-03790W Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO03790W 100 µg
MO-AB-18489W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO18489W 100 µg
MO-AB-69972W Monoclonal Silkworm (Bombyx mori) WB, ELISA MO69972W 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFruit fly (Drosophila melanogaster), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Medaka (Oryzias latipes), Rhesus (Macaca mulatta), Silkworm (Bombyx mori)
CloneMO21034FYA
SpecificityThis antibody binds to fruit fly Incenp.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationCytoskeleton; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionIn mammalian cells, 2 broad groups of centromere-interacting proteins have been described: constitutively binding centromere proteins and 'passenger,' or transiently interacting, proteins (reviewed by Choo, 1997). The constitutive proteins include CENPA (centromere protein A; MIM 117139), CENPB (MIM 117140), CENPC1 (MIM 117141), and CENPD (MIM 117142). The term 'passenger proteins' encompasses a broad collection of proteins that localize to the centromere during specific stages of the cell cycle (Earnshaw and Mackay, 1994 [PubMed 8088460]). These include CENPE (MIM 117143); MCAK (MIM 604538); KID (MIM 603213); cytoplasmic dynein (e.g., MIM 600112); CliPs (e.g., MIM 179838); and CENPF/mitosin (MIM 600236). The inner centromere proteins (INCENPs) (Earnshaw and Cooke, 1991 [PubMed 1860899]), the initial members of the passenger protein group, display a broad localization along chromosomes in the early stages of mitosis but gradually become concentrated at centromeres as the cell cycle progresses into mid-metaphase. During telophase, the proteins are located within the midbody in the intercellular bridge, where they are discarded after cytokinesis (Cutts et al., 1999 [PubMed 10369859]).
Product OverviewMouse Anti-D. melanogaster Incenp Antibody is a mouse antibody against Incenp. It can be used for Incenp detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesRE52507p; Fragment; Incenp
UniProt IDQ8IGP7
Protein RefseqThe length of the protein is 781 amino acids long.
The sequence is show below: LPPFEKNDKIEGTESGFAVCQIQSLDMEDILGVLGSLSDLRRELEVLRKAHFEELDHLFYGTGQPEAEAKPRDSAPAAKSQENSSVTPQQTKKRPKRLTSLAEDQNEPEAPDATANNTSARQSTRVSNSQLLAIAEDEHNSTASLMPPPPVPVSADTTLGSGRPQRAAKLKTEKLLKEPSLNRKMRRPSSEELVKVKVESEQRVSQFNSFTSAQALEENKLAEPELEEPAAETAEQQKPPEEASVTEDVNTTKTLRVKVKREKLSTEAVPPLTNAVSTANVTTVSSVTTEAARPDDTVASNTTTSTEVSKKVRKKKKDVESHRPIKVERFSDLDKSSPVSSRTRKCSSDSRTVQERSIYKDALEDPPVAEQSVAAVAPAAVNETVAISNATLVLGPAPTSDSPIGPAGDATFEVHSNDKKQPLSKQDSLLTEDESVEEKLPTTKLLSSIKAIKLPTRTHELFNPLLQSPVKMRVEAFENAANAQNSMRPKRGKDLQGTPGSNNTPKIGKLPAPTVGRFFTPTQTTSTLPLSSAQPKKGPASASKATSLLKTATGTNLRSVNSTSTKTLSRENSGDDFRKGLHNLAEERKKLREQKHQQAAQQREAKERERAERMAKLAAERAKKQEERKRIEERKRQELEELQRKMRQQEEAEALKKAKFKELEQQKLQQLTGAKPKKMLPPPPKTKYTWEMLHEDDSTDDEGKVTHKRPPAPTWSRSHVRGEAIAMQSHCPTDIIDSFFSVAPTTPDLKQIFPNIDPSQLKRNSSVLWSTPPRYSELPKY.
For Research Use Only | Not For Clinical Use.
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