Cat: MO-NAB-00430W
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- Product Details
Specifications
| Host species | Rabbit (Oryctolagus cuniculus) |
| Species Reactivity | Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Zebrafish (Danio rerio) |
| Clone | NW0355 |
| Specificity | This antibody is binds to Human ITGB1 and has cross reactivity with Mouse, Rat, Zebrafish. |
| Immunogen | Human integrin β1/CD29 aa 21-250 recombinant protein. |
| Epitope | The epitope is in the AA 21-250 of ITGB1. |
| Format | Liquid |
| Buffer | TBS, pH7.4, 1% BSA, 40% Glycerol. |
| Storage | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Purification | Protein A purified |
| Cellular Localization | Cell Membrane; Cell projection; Cleavage furrow |
Application Information
| Application | WB, IHC, IHC-P |
| Application Notes | Western Blot: 1:500-1:5000 Immunohistochemistry-Paraffin: 1:50-1:200 |
Target
| Introduction | Integrin β-1 (ITGB1), also known as CD29, is a cell surface receptor encoded by the ITGB1 gene. The integrin binds to integrin α1 and integrin α2 to form an integrin complex that functions as a collagen receptor. It also forms a dimer with integrin α3, thereby forming integrin receptors for netrin 1 and reelin. These and other integrin β1 complexes have historically been called very late activation (VLA) antigens.Integrin β1 is expressed as at least four different isoforms. In cardiac and skeletal muscles, integrin β-1D isoforms are specifically expressed and located in the ribs, where they contribute to the lateral force transmission from the Z disk to the extracellular matrix. Abnormal levels of integrin β-1D were found in limb-girdle muscular atrophy and polyneuropathy. |
| Product Overview | This product is a Rabbit antibody against the AA 21-250 of the ITGB1. It can be used for ITGB1 detection in Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin. |
| Alternative Names | ITGB1; CD29; FNRB; GPIIA; MDF2; MSK12; VLA-BETA; VLAB; integrin subunit beta 1 |
| Gene ID | 3688(Human); 16412(Mouse) |
| UniProt ID | P05556(Human); P09055(Mouse) |
See other products for " ITGB1 "
| MO-AB-26750R | Mouse Anti-Pig ITGB1 Antibody (MO-AB-26750R) |
| CBMOAB-00063FYA | Mouse Anti-Cattle ITGB1 Antibody (CBMOAB-00063FYA) |
| MO-AB-57416W | Mouse Anti-Marmoset ITGB1 Antibody (MO-AB-57416W) |
| MO-AB-57415W | Mouse Anti-Marmoset ITGB1 Antibody (MO-AB-57415W) |
| MO-AB-06583Y | Mouse Anti-O. anatinus ITGB1 Antibody (MO-AB-06583Y) |
| CBMOAB-45642FYA | Mouse Anti-Rhesus ITGB1 Antibody (CBMOAB-45642FYA) |
| MO-AB-00772R | Mouse Anti-Medaka itgb1 Antibody (MO-AB-00772R) |
| MO-AB-08521Y | Mouse Anti-Rabbit ITGB1 Antibody (MO-AB-08521Y) |
| MO-AB-00678L | Mouse Anti-Elephant ITGB1 Antibody (MO-AB-00678L) |
| CBMOAB-00263FYA | Rabbit Anti-Mouse ITGB1 Antibody (CBMOAB-00263FYA) |
For Research Use Only | Not For Clinical Use.