Mouse Anti-KCTD6 Antibody (CBMOAB-45996FYA)
Cat: CBMOAB-45996FYA
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
| Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
| CBMOAB-45996FYA | Monoclonal | Rhesus (Macaca mulatta), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Marmoset, Rat (Rattus norvegicus), Zebrafish (Danio rerio) | WB, ELISA | MO45996FYA | 100 µg | ||
| CBMOAB-81781FYA | Monoclonal | Zebrafish (Danio rerio) | WB, ELISA | MO81781FYA | 100 µg | ||
| MO-AB-14503R | Monoclonal | Cattle (Bos taurus) | WB, ELISA | MO14503R | 100 µg | ||
| MO-AB-15063W | Monoclonal | Chimpanzee (Pan troglodytes) | WB, ELISA | MO15063W | 100 µg | ||
| MO-AB-26632H | Monoclonal | Rat (Rattus norvegicus) | WB, ELISA | MO26632C | 100 µg | ||
| MO-AB-57695W | Monoclonal | Marmoset | WB, ELISA | MO57695W | 100 µg |
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Rhesus (Macaca mulatta), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Marmoset, Rat (Rattus norvegicus), Zebrafish (Danio rerio) |
| Clone | MO45996FYA |
| Specificity | This antibody binds to Rhesus KCTD6. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1; the function seems to depend on KCTD11:KCTD6 oligomerization. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1; the function probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medulloblastoma (MDB) (PubMed:21472142). Involved in regulating protein levels of ANK1 isoform Mu17 probably implicating CUL3-dependent proteasomal degradation (PubMed:22573887). (From uniprot, under CC BY 4.0) |
| Product Overview | Mouse Anti-Rhesus KCTD6 Antibody is a mouse antibody against KCTD6. It can be used for KCTD6 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | KCTD6 |
| UniProt ID | F7H0P7 |
| Protein Refseq | The length of the protein is 230 amino acids long. The sequence is show below: FQMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEVVELSSTRKLSKYSNPVAVIITQLTITTKVHSLLEGISNYFTKWNKHMMDTRDCQVSFTFGPCDYHQEVSLRVHLMEYITKQGFTIRNTRVHHMSERANENTVEHNWTFCRLARKTDD. |
For Research Use Only | Not For Clinical Use.
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