AibGenesis™ Mouse Anti-lin28a Antibody (CBMOAB-82765FYA)

Name: AibGenesis™ Mouse Anti-lin28a Antibody (CBMOAB-82765FYA)
SKU: CBMOAB-82765FYA
Rating: 5 (1 reviews)

Cat: CBMOAB-82765FYA

Certificate of Analysis Lookup
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Lot Number

Product List
Specifications
Application Information
Target

Sub Cat	Clonality	Species Reactivity	Application	Clone	Conjugate	Size
CBMOAB-82765FYA	Monoclonal	Zebrafish (Danio rerio), Cat (Felis catus), Frog (Xenopus laevis), Goat (Capra hircus), Marmoset, Rat (Rattus norvegicus), Sheep (Ovis aries)	WB, ELISA	MO82765FYA		100 µg	Inquiry
Protein Refseq: The length of the protein is 202 amino acids long. The sequence is show below: MPPANPHLNHTGGCTKTEEEEAASSEEDSGSFHGSGVCKWFNVRMGFGFLSMTHREGICLDSPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKRSSKGLESLQVTGPGGAPCVGSEKKPKGTQKRRSKGDRCFNCGGPNHHAKECQLPPQPKKCHFCQSISHMVANCPIKAQQLSPGSQGKSTTSTGEEEDMSHTPLLPESTD.
MO-AB-04865H	Monoclonal	Frog (Xenopus laevis)	WB, ELISA	MO04865C		100 µg	Inquiry
Protein Refseq: The length of the protein is 195 amino acids long. The sequence is show below: MGSVSNQEITEGLPKSLDGTADIHKSDKSVIFQGSGVCKWFNVRMGFGFLTMTKKEGTDLETPLDVFVHQSKLHMEGFRSLKEGESVEFTFKKSSKGLESTQVTGPGGAPCIGSERRPKVKGQQKRRQRGDRCYNCGGLDHHAKECKLPPQPKKCHFCQNPNHMVAQCPEKAMQAANLEDQPITEEQELIPEIME.
MO-AB-08540W	Monoclonal	Cat (Felis catus)	WB, ELISA	MO08540W		100 µg	Inquiry
Protein Refseq: The length of the protein is 206 amino acids long. The sequence is show below: MGSVSNQQFAGGCAKAPEEAPEDAARAAEEPQLLHGAGICKWFNVRMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSAKGLESIRVTGPGGVFCIGSERRPKGKNMQKRRSKGDRCYNCGGLDHHAKECKLPPQPKKCHFCQSISHMVASCPLKAQQAPSSQGKPAYFREEEEEEIHSPALLPEAQN.
MO-AB-16044Y	Monoclonal	Sheep (Ovis aries)	WB, ELISA	MO16044Y		100 µg	Inquiry
Protein Refseq: The length of the protein is 209 amino acids long. The sequence is show below: MGSVSNQQFAGGCAKAPEEAPEEAPEDAARAAEEPQLLHGAGICKWFNVRMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSAKGLESIRVTGPGGVFCIGSERRPKGKNVQKRRSKGDRCYNCGGLDHHAKECKLPPQPKKCHFCQSISHMVASCPLKAQQAPSSQGKPAYFREEEEEIHSSAMLPEAQN.
MO-AB-26802H	Monoclonal	Rat (Rattus norvegicus)	WB, ELISA	MO26802C		100 µg	Inquiry
Protein Refseq: The length of the protein is 209 amino acids long. The sequence is show below: MGSVSNQQFAGGCAKAAEKAPEEAPADAARAADEPQLLHGAGICKWFNVRMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSAKGLESIRVTGPGGVFCIGSERRPKGKSMQKRRSKGDRCYNCGGLDHHAKECKLPPQPKKCHFCQSISHMVASCPLKAQQGPSSQGKPVYFREEEEEIHSPTLLPEAQN.
MO-AB-37614W	Monoclonal	Goat (Capra hircus)	WB, ELISA	MO37614W		100 µg	Inquiry
Protein Refseq: The length of the protein is 209 amino acids long. The sequence is show below: MGSVSNQQFAGGCAKAPEEAPEEAPEDAARAAEEPQLLHGAGICKWFNVCMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSAKGLESIRVTGPGGVFCIGSERRPKGKNVQKRRSKGDRCYNCGGLDHHAKECKLPPQPKKCHFCQSISHMVASCPLKAQQAPSSQGKPAYFREEEEEIHSSAMLPETQN.
MO-AB-58216W	Monoclonal	Marmoset	WB, ELISA	MO58216W		100 µg	Inquiry
Protein Refseq: The length of the protein is 208 amino acids long. The sequence is show below: MGSVSNQQFAGGCAKVAEEAPEEAPADAARAADEPQLLHGAGICKWFNVRMGFGFLSMTARARVALDPPVNVFVHQSKLHMEGFRSLKEGEAVEFTFKKSAKGLESIHVTGPGGVFCIGSDRPPKGKNRQKRRSKGDRCYNCGGLDHHAKEYKLPPQPKKCHFYQSISHMVASCPLKAQQAPKAQGKPKYFREEEEIHSPALLPEAQN.

Specifications

Host species	Mouse (Mus musculus)
Species Reactivity	Zebrafish (Danio rerio), Cat (Felis catus), Frog (Xenopus laevis), Goat (Capra hircus), Marmoset, Rat (Rattus norvegicus), Sheep (Ovis aries)
Clone	MO82765FYA
Specificity	This antibody binds to Zebrafish lin28a.
Format	Liquid or Lyophilized
Storage	Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use
Purity	> 90% was determined by SDS-PAGE
Purification	Purified with Protein A or G affinity chromatography
Cellular Localization	Nucleus; Endoplasmic reticulum; Other locations

Application Information

Application	WB, ELISA
Application Notes	ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

Introduction	RNA-binding protein that inhibits processing of pre-let-7 miRNAs and regulates translation of mRNAs that control developmental timing, pluripotency and metabolism. Seems to recognize a common structural G-quartet (G4) feature in its miRNA and mRNA targets. 'Translational enhancer' that drives specific mRNAs to polysomes and increases the efficiency of protein synthesis. Its association with the translational machinery and target mRNAs results in an increased number of initiation events per molecule of mRNA and, indirectly, in mRNA stabilization. Suppressor of microRNA (miRNA) biogenesis, including that of let-7. Binds specific target miRNA precursors (pre-miRNAs), recognizing an 5'-GGAG-3' motif found in their terminal loop, and recruits uridylyltransferase. This results in the terminal uridylation of target pre-miRNAs. Uridylated pre-miRNAs fail to be processed by Dicer and undergo degradation. Localized to the periendoplasmic reticulum area, binds to a large number of spliced mRNAs and inhibits the translation of mRNAs destined for the ER, reducing the synthesis of transmembrane proteins, ER or Golgi lumen proteins, and secretory proteins. Binds to and enhances the translation of mRNAs for several metabolic enzymes, increasing glycolysis and oxidative phosphorylation. Which, with the let-7 repression may enhance tissue repair in adult tissue. (From uniprot, under CC BY 4.0)
Product Overview	Mouse Anti-Zebrafish lin28a Antibody is a mouse antibody against lin28a. It can be used for lin28a detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative Names	Protein lin-28 homolog A; Lin-28A; lin28a; lin2
UniProt ID	Q803L0
Protein Refseq	The length of the protein is 202 amino acids long. The sequence is show below: MPPANPHLNHTGGCTKTEEEEAASSEEDSGSFHGSGVCKWFNVRMGFGFLSMTHREGICLDSPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKRSSKGLESLQVTGPGGAPCVGSEKKPKGTQKRRSKGDRCFNCGGPNHHAKECQLPPQPKKCHFCQSISHMVANCPIKAQQLSPGSQGKSTTSTGEEEDMSHTPLLPESTD.

For Research Use Only | Not For Clinical Use.

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