Mouse Anti-Marmoset MBD3 Antibody (MO-AB-58806W)


Cat: MO-AB-58806W
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityMarmoset
CloneMO58806W
SpecificityThis antibody binds to Marmoset MBD3.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionDNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. This gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD). The encoded protein is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. Alternative splicing results in multiple transcript variants of this gene.
Product OverviewMouse Anti-Marmoset MBD3 Antibody is a mouse antibody against MBD3. It can be used for MBD3 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesMethyl-CpG-binding domain protein 3; MBD3
UniProt IDU3DNG4
Protein RefseqThe length of the protein is 290 amino acids long.
The sequence is show below: MERKRWECPALPQGWEREEVPRRSGLSAGHRDVFYYSPSGKKFRSKPQLARYLGGSMDLSTFDFRTGKMLMSRMNKSRQRVRYDSSNQVKGKPDLNTALPVRQTASIFKQPVTKITNHPSNKVKSDPQKAVDQPRQLFWEKKLSGLNAFDIAEELVKTMDLPKGLQGVGPGCTDETLLSAIASALHTSTMPITGQLSAAVEKNPGVWLNTTQPLCKAFMVTDEDIRKQEELVQQVRKRLEEALMADMLAHVEELSRDGEAPLDKACTEDDEEDEDEEEEEPDPDPEMEHV.
For Research Use Only | Not For Clinical Use.
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