Mouse Anti-Medaka mdh1 Antibody (MO-AB-00877R)
Cat: MO-AB-00877R
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Medaka (Oryzias latipes) |
Clone | MO00877R |
Specificity | This antibody binds to Medaka mdh1. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Cytosol |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | This gene encodes an enzyme that catalyzes the NAD/NADH-dependent, reversible oxidation of malate to oxaloacetate in many metabolic pathways, including the citric acid cycle. Two main isozymes are known to exist in eukaryotic cells: one is found in the mitochondrial matrix and the other in the cytoplasm. This gene encodes the cytosolic isozyme, which plays a key role in the malate-aspartate shuttle that allows malate to pass through the mitochondrial membrane to be transformed into oxaloacetate for further cellular processes. Alternatively spliced transcript variants have been found for this gene. A recent study showed that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Pseudogenes have been identified on chromosomes X and 6. |
Product Overview | This product is a mouse antibody against mdh1. It can be used for mdh1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Malate dehydrogenase; EC 1.1.1.37; mdha |
UniProt ID | H2LCJ4 |
Protein Refseq | The length of the protein is 392 amino acids long. The sequence is show below: MLTLLTSMYMVVRAISPQVTIQVLMKTPPPPPKXKKRHLCPVTAEAEPIRVVVTGAAGQIAYSLLFSIAKGDVFGKDQPIILILLDIPPMLPVLDGVVMELQDCALPLLRASSPLKPSAVVKTTTEVIPTDKVEVGFKDIDAAILVGSMPRKEGMERKDLLKANVAIFKTQGQALDKYAKKTVKVLVVGNPANTNCLIASKSAPSIPKENFSCLTRLDHNRACSQVAMRCGVSSDKVKNVIIWGNHSSTQYPDVHHAKVNVSGSEVSAYDAVKNDAWLRGDFISTVQLRGAAVIKARKLSSAMSAAKAICDHMRDIWFGTKEGEFISMGVYAAGNSYGIPEDLIYSFPIQIKNKTWKVVDGLPINDFSRAKMDATAAELVEERDTAMDFLSQ. |
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For Research Use Only | Not For Clinical Use.
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