Rabbit Anti-Mouse S100B Antibody (CBMOAB-00281FYA)

Cat: CBMOAB-00281FYA
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Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Goat (Capra hircus), Zebrafish (Danio rerio)
SpecificityThis antibody is binds to Mouse S100B and has cross reactivity with Human, Rat, Goat, Zebrafish.
BufferTBS, pH 7.4
PurificationPurified with Protein A affinity chromatography
Cellular LocalizationCytoplasm; Nucleus

Application Information

ApplicationWB, IF, IP, IHC
Application NotesWB: 1:1,000-1:5,000
ICC: 1:50-1:200
IHC: 1:50-1:200


IntroductionThe protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
Product OverviewRabbit Anti-Mouse S100B (clone F00281FYA) Antibody (CBMOAB-00281FYA) is a Rabbit antibody against the S100B. It can be used for S100B detection in Western Blot, Immunofluorescence, Immunoprecipitation, Immunohistochemistry.
Alternative NamesS100 Calcium Binding Protein B; S-100 Protein Subunit Beta; S100 Calcium Binding Protein, Beta (Neural); S100 Calcium-Binding Protein, Beta (Neural); S-100 Calcium-Binding Protein, Beta Chain; S100 Calcium-Binding Protein B; S-100 Protein Beta Chain
Gene ID6285
UniProt IDP04271
For Research Use Only | Not For Clinical Use.

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