Rabbit Anti-MRPL10 Antibody (MO-DKB-01324W)


Cat: MO-DKB-01324W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityHuman (Homo sapiens), Bovine (Bos taurus), Rhesus (Macaca mulatta)
ImmunogenA recombinant protein containing sequences in the central region of human MRPL10.
EpitopeThe epitope is in the Center of MRPL10.
FormatLiquid or Lyophilized
Buffer0.1M Tris, pH 7, 0.1M Glycine, 20% Glycerol
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurityAffinity purified
Cellular LocalizationMitochondrion

Application Information

ApplicationWB, IHC, IHC-P
Application NotesWestern Blot 1:500-1:3000
Immunohistochemistry 1:100-1:1000
Immunohistochemistry-Paraffin 1:100-1:1000

Target

IntroductionMammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode two different isoforms. A pseudogene corresponding to this gene is found on chromosome 5q. [provided by RefSeq, Nov 2010]
Product OverviewThis product is a Rabbit antibody against the Center of the MRPL10. It can be used for MRPL10 detection in Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.
Alternative NamesMitochondrial Ribosomal Protein L10; Mitochondrial Large Ribosomal Subunit Protein UL10m; 39S Ribosomal Protein L10, Mitochondrial; 39S Ribosomal Protein L8, Mitochondrial; MRP-L10; MRP-L8;
Gene ID124995
UniProt IDQ7Z7H8
For Research Use Only | Not For Clinical Use.
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