Rabbit Anti-OPA1 (AA 500-600) Antibody (Cat MO-DKB-03138W)


Cat: MO-DKB-03138W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Pig (Sus scrofa), Chicken (Gallus gallus), Zebrafish (Danio rerio), Primate
SpecificityThis antibody is binds to Human OPA1 and has cross reactivity with Mouse, Rat, Pig, Chicken, Zebrafish, Primate OPA1.
ImmunogenA synthetic peptide made in the internal region within residues 500-600 of human OPA1.
EpitopeAA 500-600
FormatLiquid or Lyophilized
BufferPBS
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationAffinity purified
Cellular LocalizationMitochondrion, Mitochondrial Inner Membrane, Single-Pass Membrane Protein, Mitochondrion, Mitochondrial Intermembrane Space.

Application Information

ApplicationWB, IB, IHC, IHC-P
Application NotesWestern Blot: 2 ug/mL
Simple Western: 20 ug/mL
Immunohistochemistry: 2.5 ug/mL
Immunohistochemistry-Paraffin: 2.5 ug/mL
The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. The encoded protein localizes to the inner mitochondrial membrane and helps regulate mitochondrial stability and energy output. This protein also sequesters cytochrome c. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness.
Product OverviewThis product is a Rabbit antibody against the OPA1. It can be used for OPA1 detection in Western Blot, Immunoblotting, Immunohistochemistry, Immunohistochemistry-Paraffin.
Alternative NamesDynamin-like 120 kDa protein, mitochondrial; opa
UniProt IDF1QB88
For Research Use Only | Not For Clinical Use.
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