Mouse Anti-PDK3 Antibody (CBMOAB-54177FYA)
Cat: CBMOAB-54177FYA
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
| Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
| CBMOAB-54177FYA | Monoclonal | Rhesus (Macaca mulatta), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Marmoset, Pig (Sus scrofa) | WB, ELISA | MO54177FYA | 100 µg | ||
| MO-AB-05077W | Monoclonal | Rhesus (Macaca mulatta) | WB, ELISA | MO05077W | 100 µg | ||
| MO-AB-17720R | Monoclonal | Cattle (Bos taurus) | WB, ELISA | MO17720R | 100 µg | ||
| MO-AB-22690W | Monoclonal | Chimpanzee (Pan troglodytes) | WB, ELISA | MO22690W | 100 µg | ||
| MO-AB-28186R | Monoclonal | Pig (Sus scrofa) | WB, ELISA | MO28186R | 100 µg | ||
| MO-AB-61241W | Monoclonal | Marmoset | WB, ELISA | MO61241W | 100 µg |
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Rhesus (Macaca mulatta), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Marmoset, Pig (Sus scrofa) |
| Clone | MO54177FYA |
| Specificity | This antibody binds to Rhesus PDK3. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Mitochondrion |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle, and thus is one of the major enzymes responsible for the regulation of glucose metabolism. The enzymatic activity of PDH is regulated by a phosphorylation/dephosphorylation cycle, and phosphorylation results in inactivation of PDH. The protein encoded by this gene is one of the three pyruvate dehydrogenase kinases that inhibits the PDH complex by phosphorylation of the E1 alpha subunit. This gene is predominantly expressed in the heart and skeletal muscles. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. (From NCBI) |
| Product Overview | Mouse Anti-Rhesus PDK3 Antibody is a mouse antibody against PDK3. It can be used for PDK3 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | PDK3 |
| UniProt ID | F6PXB7 |
| Protein Refseq | The length of the protein is 404 amino acids long. The sequence is show below: MRLFRWLLKQPVPKQIERYSRFSPSPLSIKQFLDFGRDNACEKTSYMFLRKELPVRLANTMREVNLLPDNLLNRPSVGLVQSWYMQSFLELLEYENKSPEDPQVLDNFLQVLIKVRRHNDVVPTMAQGVTIVISPKCFPVVNLLTCIFGCRNFISSLVFQLLTHQLSLLFGGDTNPVHPKHIGSIDPTCNVADVVKDAYETAKMLCEQYYLVAPELEVEEFNAKAPDKPIQVVYVPSHLFHMLFELFKNSMRATVELYEDRKEGYPAVKTLVTLGKEDLSIKISDLGGGVPLRKIDRLFNYMYSTAPRPSLEPTRAAPLAGFGYGLPISRLYARYFQGDLKLYSMEGVGTDAVIYLKALSSESFERLPVFNKSAWRHYKTTPEADDWSNPSSEPRDASKYKAKQ. |
For Research Use Only | Not For Clinical Use.
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