Mouse Anti-RAD23B Antibody (MOF032922W151)
Cat: MOF032922W151
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- Product Details
Specifications
Host species | Mouse |
Species Reactivity | Human, Mouse, Rat, Monkey, Hamster |
Specificity | This antibody detects endogenous levels of hHR23b and does not cross-react with related proteins. |
Immunogen | Purified recombinant human hHR23b protein fragment expressed in E. coli. |
Format | Liquid or Lyophilized |
Buffer | PBS pH 7.3, 50% glycerol, 0.5% BSA |
Regulatory Status | For Research Use Only. Not For Clinical Use. |
Shipping | Gel Pack |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 95% was determined by SDS-PAGE |
Purification | Affinity Purified |
Cellular Localization | Cytoplasm, Nucleus, Proteasome |
Application Information
Application | WB, IHC-Fr, IHC-P, ICC/IF |
Application Notes | WB: 1/1000 IHC: 1/100 ICC: 1/100 The optimal dilution should be determined by the end user. |
Target
Introduction | The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was found to be a component of a protein complex that specifically complements NER deficiency in xeroderma pigmentosum group C (XP-c) cell extracts in vitro. The protein was also shown to interact with 3-methyladenine-DNA glycosylase (MPG) and increase its nucleotide excision activity, suggesting a role in DNA damage recognition in base excision repair. The protein contains an N-terminal ubiquitin-like domain, which is reported to interact with the 26S proteasome, thus the protein may be involved in the ubiquitin-mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
Alternative Names | P58; HR23B; HHR23B. |
Gene ID | 5887 |
UniProt ID | P54727 |
See other products for " RAD23B "
CBMOAB-39748FYC | Mouse Anti-Arabidopsis RAD23B Antibody (CBMOAB-39748FYC) |
MO-AB-22409W | Mouse Anti-Chimpanzee RAD23B Antibody (MO-AB-22409W) |
MO-DKB-0444RA | Rabbit Anti-RAD23b Antibody (MO-DKB-0444RA) |
MO-AB-06867H | Mouse Anti-Frog rad23b Antibody (MO-AB-06867H) |
MO-AB-62873W | Mouse Anti-Marmoset RAD23B Antibody (MO-AB-62873W) |
CBMOAB-55963FYA | Mouse Anti-Rhesus RAD23B Antibody (CBMOAB-55963FYA) |
MO-AB-18990R | Mouse Anti-Cattle RAD23B Antibody (MO-AB-18990R) |
CBMOAB-95136FYA | Mouse Anti-Zebrafish rad23b Antibody (CBMOAB-95136FYA) |
For Research Use Only | Not For Clinical Use.
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