AibGenesis™ Mouse Anti-AKAP8L Antibody (CBMOAB-35429FYA)
Cat: CBMOAB-35429FYA
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
| Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
| CBMOAB-35429FYA | Monoclonal | Rhesus (Macaca mulatta), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Marmoset, Zebrafish (Danio rerio) | WB, ELISA | MO35429FYA | 100 µg | ||
| CBMOAB-65385FYA | Monoclonal | Zebrafish (Danio rerio) | WB, ELISA | MO65385FYA | 100 µg | ||
| MO-AB-07188R | Monoclonal | Cattle (Bos taurus) | WB, ELISA | MO07188R | 100 µg | ||
| MO-AB-25102W | Monoclonal | Chimpanzee (Pan troglodytes) | WB, ELISA | MO25102W | 100 µg | ||
| MO-AB-50660W | Monoclonal | Marmoset | WB, ELISA | MO50660W | 100 µg |
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Rhesus (Macaca mulatta), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Marmoset, Zebrafish (Danio rerio) |
| Clone | MO35429FYA |
| Specificity | This antibody binds to Rhesus AKAP8L. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Nucleus |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Could play a role in constitutive transport element (CTE)-mediated gene expression by association with DHX9. Increases CTE-dependent nuclear unspliced mRNA export (PubMed:10748171, PubMed:11402034). Proposed to target PRKACA to the nucleus but does not seem to be implicated in the binding of regulatory subunit II of PKA (PubMed:10761695, PubMed:11884601). May be involved in nuclear envelope breakdown and chromatin condensation. May be involved in anchoring nuclear membranes to chromatin in interphase and in releasing membranes from chromating at mitosis (PubMed:11034899). May regulate the initiation phase of DNA replication when associated with TMPO isoform Beta (PubMed:12538639). Required for cell cycle G2/M transition and histone deacetylation during mitosis. In mitotic cells recruits HDAC3 to the vicinity of chromatin leading to deacetylation and subsequent phosphorylation at Ser-10 of histone H3; in this function seems to act redundantly with AKAP8 (PubMed:16980585). May be involved in regulation of pre-mRNA splicing (PubMed:17594903). (From uniprot, under CC BY 4.0) |
| Product Overview | Mouse Anti-Rhesus AKAP8L Antibody is a mouse antibody against AKAP8L. It can be used for AKAP8L detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | AKAP8L |
| UniProt ID | F7DN43 |
| Protein Refseq | The length of the protein is 431 amino acids long. The sequence is show below: MSYTGFVQGSETTLQSTYSDTSAQPTCDYGYGTWNSGTNRGYEGYGYGYGYGQDNTTNYGINQRLDMVPHLETDMMQGGVYGSGGERYDSYESCDSRAVLSERDLYRSGYDYSELDPEMEMAYEGQYDAYRDQFRMRGNDTFGPRAQGWARDARSGRPMASGYGRMWEDPMGARGQCMSGASRLPSLFSQNIIPEYGMFQGMRGGGAFPGGSRFGFGFGNGMKQMRRTWKTWTTADFRTKKKKRKQGGSPDEPDSKATRTDCSDNSDSDNDEGTEGEATEGLEGTEAVEKGSRVDGEDEEGKEDGREEGKEDSEKGALTTQDENGQTKRKLQAGKKSQDKQKKRQRDRMVERAPALALASSASDSCSCWTFLSLAGARPLGSPDKADPVAQIRTSGRGSSLCVLSANTGPSMRMRWPAILTASSTRNTSST. |
For Research Use Only | Not For Clinical Use.
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