AibGenesis™ Mouse Anti-ALKBH7 Antibody (CBMOAB-35537FYA)
Cat: CBMOAB-35537FYA
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
| Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
| CBMOAB-35537FYA | Monoclonal | Rhesus (Macaca mulatta), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Marmoset, Rat (Rattus norvegicus), Zebrafish (Danio rerio) | WB, ELISA | MO35537FYA | 100 µg | ||
| CBMOAB-65572FYA | Monoclonal | Zebrafish (Danio rerio) | WB, ELISA | MO65572FYA | 100 µg | ||
| MO-AB-07263R | Monoclonal | Cattle (Bos taurus) | WB, ELISA | MO07263R | 100 µg | ||
| MO-AB-12285W | Monoclonal | Chimpanzee (Pan troglodytes) | WB, ELISA | MO12285W | 100 µg | ||
| MO-AB-24041H | Monoclonal | Rat (Rattus norvegicus) | WB, ELISA | MO24041C | 100 µg | ||
| MO-AB-50747W | Monoclonal | Marmoset | WB, ELISA | MO50747W | 100 µg |
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Rhesus (Macaca mulatta), Cattle (Bos taurus), Chimpanzee (Pan troglodytes), Marmoset, Rat (Rattus norvegicus), Zebrafish (Danio rerio) |
| Clone | MO35537FYA |
| Specificity | This antibody binds to Rhesus ALKBH7. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | May function as protein hydroxylase; can catalyze auto-hydroxylation at Leu-110 (in vitro), but this activity may be due to the absence of the true substrate (PubMed:25122757). Required to induce programmed necrosis in response to DNA damage caused by cytotoxic alkylating agents. Acts by triggering the collapse of mitochondrial membrane potential and loss of mitochondrial function that leads to energy depletion and cell death (PubMed:23666923). ALKBH7-mediated necrosis is probably required to prevent the accumulation of cells with DNA damage (PubMed:23666923). Does not display DNA demethylase activity (PubMed:23666923). Involved in fatty acid metabolism. (From uniprot, under CC BY 4.0) |
| Product Overview | Mouse Anti-Rhesus ALKBH7 Antibody is a mouse antibody against ALKBH7. It can be used for ALKBH7 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | ALKBH7 |
| UniProt ID | F7HMA8 |
| Protein Refseq | The length of the protein is 221 amino acids long. The sequence is show below: MAATGLLALRTLPGPSWVRGSGPSVLSRLRDAAVVRPGFLSTAEEETLNRELEPELRRRRYEYDHWDAAIHGFRETEKWRWSEASRAILQRVQAAAFGPGQTPLSSVHVLDLEARGYIKPHVDSIKFCGATIAGLSLLSPSVMRLVHTQDPGEWLELLLEPGSLYILRGSARYDFSHEILRDEESFFGERRIPRGRRISVICRSLPEGMGPGESGQPPPAC. |
For Research Use Only | Not For Clinical Use.
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