AibGenesis™ Mouse Anti-AUNIP Antibody (CBMOAB-36650FYA)


Cat: CBMOAB-36650FYA

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Lot Number

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Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-36650FYA Monoclonal Rhesus (Macaca mulatta), Cattle (Bos taurus) WB, ELISA MO36650FYA 100 µg
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MO-AB-07897R Monoclonal Cattle (Bos taurus) WB, ELISA MO07897R 100 µg
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRhesus (Macaca mulatta), Cattle (Bos taurus)
CloneMO36650FYA
SpecificityThis antibody binds to Rhesus AUNIP.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationCytoskeleton; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionDNA-binding protein that accumulates at DNA double-strand breaks (DSBs) following DNA damage and promotes DNA resection and homologous recombination (PubMed:29042561). Serves as a sensor of DNA damage: binds DNA with a strong preference for DNA substrates that mimic structures generated at stalled replication forks, and anchors RBBP8/CtIP to DSB sites to promote DNA end resection and ensuing homologous recombination repair (PubMed:29042561). Inhibits non-homologous end joining (NHEJ) (PubMed:29042561). Required for the dynamic movement of AURKA at the centrosomes and spindle apparatus during the cell cycle (PubMed:20596670). (From uniprot, under CC BY 4.0)
Product OverviewMouse Anti-Rhesus AUNIP Antibody is a mouse antibody against AUNIP. It can be used for AUNIP detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesAUNIP
UniProt IDF7BDG2
Protein RefseqThe length of the protein is 351 amino acids long.
The sequence is show below: MRRTGPEEEACGVWLDAAALKRRKVQTHLIKPGTKMLTLLPGERKASIYFTQRRAPSTGIHQRSIASFFTLQPGKTNGSDQKSVSSHTESQLNKESKKNVTQLDHLIPGLAHDCMISPLATSTTADIQEAGLSPQSLQTSGHHRTELSLLQPDTLDCAGESNTPLAFSFTEDLESSCLLDQKEEKGDSARKWEWLHGSKKNCHSMKKYTKLPGDKCCQPLGKTKLERKVSAKENRQAPVLLQTYRESWNGENVESVKQSSCPVSVFSWDNENNDKDSWSQLFTEDSQGQRVIAHNTRAPFQDVTNNWNWDLGPFPDSSWTQCQEDGPTQNLKPDLLFTQDSEGNQVIRHQF.
For Research Use Only | Not For Clinical Use.
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