Mouse Anti-Rhesus CD3 Antibody (MO-NAB-00068W)
Cat: MO-NAB-00068W
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Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Rhesus (Macaca mulatta), Cynomolgus (Macaca fascicularis), African green monkey |
| Clone | NW0022 |
| Specificity | Mouse anti Monkey CD3 antibody, clone FN-18 recognizes the rhesus monkey RhT3 antigen, the homolog of human CD3. Mouse anti Monkey CD3 antibody, clone FN-18 has been reported to recognize a polymorphic epitope of the RhT3 antigen, which is expressed by mature T lymphocytes. |
| Immunogen | Rhesus monkey peripheral blood white blood cells. |
| Format | Liquid or Lyophilized |
| Buffer | PBS, 1% BSA, 125mM Trehalose |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purification | Ion exchange chromatography |
Application Information
| Application | FC |
| Application Notes | FC: 1/10 |
Target
| Introduction | CD3 (cluster of differentiation 3) is a protein complex and T cell co-receptor that is involved in activating both the cytotoxic T cell (CD8+ naive T cells) and T helper cells (CD4+ naive T cells). It is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. |
| Product Overview | Mouse Anti-Rhesus CD3 (clone NW0022) Antibody (MO-NAB-00068W) is a Mouse antibody against the epitope of the CD3. It can be used for CD3 detection in Flow Cytometry. |
| Alternative Names | Cluster of differentiation 3; CD3 |
Reference
| Reference | 1. Thomas, J. M., Neville, D. M., Contreras, J. L., Eckhoff, D. E., Meng, G., Lobashevsky, A. L., ... & Thomas, F. T. (1997). PRECLINICAL STUDIES OF ALLOGRAFT TOLERANCE IN RHESUS MONKEYS: A Novel Anti-CD3-Immunotoxin Given Peritransplant with Donor Bone Marrow Induces Operational Tolerance to Kidney Allografts: 1. Transplantation, 64(1), 124-135. 2. Dykhuizen, M., Ceman, J., Mitchen, J., Zayas, M., MacDougall, A., Helgeland, J., ... & Pauza, C. D. (2000). Importance of the CD3 marker for evaluating changes in rhesus macaque CD4/CD8 T-cell ratios. Cytometry: The Journal of the International Society for Analytical Cytology, 40(1), 69-75. |
See other products for " CD3 "
| CBMOAB-00070FYA | Mouse Anti-Bison CD3 Antibody (CBMOAB-00070FYA) |
| CBMOAB-00071FYA | Mouse Anti-Bison CD3 Antibody (CBMOAB-00071FYA) |
| MOFY-0522-FY1 | Mouse Anti-CD3 Antibody (MOFY-0522-FY1) |
Figure 1 Changes of T cells and B cells in PBL after peritransplant anti-CD3-IT treatment. Results were expressed as percentage of pretransplant values. T cells decreased on day +1 in all groups, and significant recovery began around day 7.
For Research Use Only | Not For Clinical Use.
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