Mouse Anti-Rhesus CD68 Antibody (MO-AB-01564W)


Cat: MO-AB-01564W
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRhesus (Macaca mulatta)
CloneMO01564W
SpecificityThis antibody binds to Rhesus CD68.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationOther locations; Lysosome

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionCD68 (CD68 Molecule) is a Protein Coding gene. Diseases associated with CD68 include Granular Cell Tumor and Breast Granular Cell Tumor. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Innate Immune System. An important paralog of this gene is LAMP1.
Product OverviewMouse Anti-Rhesus CD68 Antibody is a mouse antibody against CD68. It can be used for CD68 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesMacrosialin isoform A; CD68
UniProt IDH9ZFR5
Protein RefseqThe length of the protein is 324 amino acids long.
The sequence is show below: MRLAVLFLGALLGLLAAQGTGNDCPHKKSATLLPSFTVTPTATESTGTTSHRTTKSHKTTTHRTTTTGTTSHRPTTATHNPTTTSHRNATVHPTSNSTATSQGPTSSAHPGPPPPSPSPSPASKETIGDYMWTNGSQPCVHLQAQIQIRVMYTTQGGGEAWGISVLNPNKTKVQGSCEGAHPHLLLSFPYGHLSFGFMQDLQQRVVYLSYMAVEYNVSFPHAAQWTFSAQNASLRDLQAPLGQSFSCSNSSIILSPAVHLDLLSLRLQAAQLPHTGVFGQSFSCPSDRSILLPLIIGLVLLGLLALVLIAFCIVRRRPSAYQAL.

Reference

ReferenceMakori, N., Tarantal, A. F., Lü, F. X., Rourke, T., Marthas, M. L., McChesney, M. B., ... & Miller, C. J. (2003). Functional and morphological development of lymphoid tissues and immune regulatory and effector function in Rhesus monkeys: Cytokine-secreting cells, immunoglobulin-secreting cells, and CD5+ B-1 cells appear early in fetal development. Clinical and Vaccine Immunology, 10(1), 140-153.

Figure 1 Jejunums, ileums, and colons of fetal rhesus monkeys. At day 65 of gestation, macrophages were few, while p55+ DCs were numerous throughout the gut lamina propria, especially at the tips of villi.

For Research Use Only | Not For Clinical Use.
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