AibGenesis™ Mouse Anti-GPR124 Antibody (CBMOAB-43920FYA)
Cat: CBMOAB-43920FYA
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
| Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
| CBMOAB-43920FYA | Monoclonal | Rhesus (Macaca mulatta), Chimpanzee (Pan troglodytes), Marmoset, Zebrafish (Danio rerio) | WB, ELISA | MO43920FYA | 100 µg | ||
| CBMOAB-78431FYA | Monoclonal | Zebrafish (Danio rerio) | WB, ELISA | MO78431FYA | 100 µg | ||
| MO-AB-18089W | Monoclonal | Chimpanzee (Pan troglodytes) | WB, ELISA | MO18089W | 100 µg | ||
| MO-AB-56266W | Monoclonal | Marmoset | WB, ELISA | MO56266W | 100 µg |
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Rhesus (Macaca mulatta), Chimpanzee (Pan troglodytes), Marmoset, Zebrafish (Danio rerio) |
| Clone | MO43920FYA |
| Specificity | This antibody binds to Rhesus GPR124. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Endothelial receptor which functions together with reck to enable brain endothelial cells to selectively respond to Wnt7 signals (wnt7a or wnt7b) (PubMed:26051822, PubMed:30026314). Plays a key role in Wnt7-specific responses: Required for normal central nervous system (CNS) vascularization where it functions cell-autonomously in the tip cells of sprouting vessels (PubMed:26051822). Has a role in development of dorsal root ganglia (PubMed:26051822). Acts as a Wnt7-specific coactivator of canonical Wnt signaling: required to deliver reck-bound Wnt7 to frizzled by assembling a higher-order RECK-ADGRA2-Fzd-LRP5-LRP6 complex (PubMed:30026314). Adgra2-tethering function does not rely on its G-protein coupled receptor (GPCR) structure but instead on its combined capacity to interact with RECK extracellularly and recruit the Dishevelled scaffolding protein intracellularly (PubMed:30026314). (From uniprot, under CC BY 4.0) |
| Product Overview | Mouse Anti-Rhesus GPR124 Antibody is a mouse antibody against GPR124. It can be used for GPR124 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | G-protein coupled receptor 124; GPR124 |
| UniProt ID | H9FHF1 |
| Protein Refseq | The length of the protein is 263 amino acids long. The sequence is show below: RRRVVCGGGDLPEPPEPGLLPNGTVTLLLSNNKITGLRNGSFLGLSLLEKLDLRNNIISTVQPGAFLGLGELKRLDLSNNRIGCLTSETFRGLPRLLRLNISGNIFSSLQPGVFDELPALKVVDLGTEFLTCDCRLRWLLPWAQNRSLQLSERTLCAYPSALHAQALGSLQEAQLCCEGALELHTHHLIPSLRQVVFQGDRLPFQCSASYLGNDTRIRWYHNRAPVEGDEQAGILLAESLIHDCTFITSELTLSHIGVWASGE. |
For Research Use Only | Not For Clinical Use.
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