Mouse Anti-Rhesus IL7R Antibody (CBMOAB-45363FYA)
Cat: CBMOAB-45363FYA
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Rhesus (Macaca mulatta) |
Clone | MO45363FYA |
Specificity | This antibody binds to Rhesus IL7R. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found. |
Product Overview | Mouse Anti-Rhesus IL7R Antibody is a mouse antibody against IL7R. It can be used for IL7R detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | IL7R |
UniProt ID | F7G3I0 |
Protein Refseq | The length of the protein is 459 amino acids long. The sequence is show below: MTILGTTFGMVFSLLQVVSGESGYAQNGDLEDAELDDYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLSFRKLQEIYFIETKKFLLIGKSNICVKVGGKSLTCKKIDLTTIVKPEAPFDLSVIYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWMHVNLSSTKLTLLQRNLQPEAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTPEINNSPGEMDPILLTISLLSFFSVALLVILACVLWKKRIKPIVWPSLPDHKKTLEHLCKKPRKNLNVSFNPESFLDCQIHRVDDIQARDEVEGFLQDTFPQQLEESKKQRLGGDVQSPSCPSEDVVITPESFERDSSLRCLAGNVSACDAPILSSSRSLDCRESGKNGPHVYQDLLLSLGTTNSTLPPPFSLPSGILTLNPVAQGQPILTSLGSNQEEAYVTMSSFYQNQ. |
Reference
Reference | 1. Cordes, S., Mortlock, R. D., Truitt, L., Yang, D., Espinoza, D. A., Fan, X., ... & Dunbar, C. E. (2021). Single Cell RNA-Seq Characterization of an Adaptive Population of NK Cells after Primary CMV Infection in Rhesus Macaques. Blood, 138, 193. 2. Schott, G., Galarza-Muñoz, G., Trevino, N., Chen, X., Weirauch, M. T., Gregory, S. G., ... & Garcia-Blanco, M. A. (2021). U2AF2 binds IL7R exon 6 ectopically and represses its inclusion. RNA, 27(5), 571-583. |
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For Research Use Only | Not For Clinical Use.
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