Mouse Anti-IL7R Antibody (CBMOAB-45363FYA)


Cat: CBMOAB-45363FYA
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Lot Number

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  • Specifications
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Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-45363FYA Monoclonal Rhesus (Macaca mulatta), Chicken (Gallus gallus), Horse (Equus caballus), Human (Homo sapiens), Zebrafish (Danio rerio), Marmoset, O. mykiss (Oncorhynchus mykiss) WB, ELISA MO45363FYA 100 µg
CBMOAB-80704FYA Monoclonal Zebrafish (Danio rerio) WB, ELISA MO80704FYA 100 µg
MO-AB-02555Y Monoclonal Chicken (Gallus gallus) WB, ELISA MO02555Y 100 µg
MO-AB-11855Y Monoclonal O. mykiss (Oncorhynchus mykiss) WB, ELISA MO11855Y 100 µg
MO-AB-45161W Monoclonal Horse (Equus caballus) WB, ELISA MO45161W 100 µg
MO-AB-57230W Monoclonal Marmoset WB, ELISA MO57230W 100 µg
MO-DKB-00339W Polyclonal Human (Homo sapiens), Zebrafish (Danio rerio) WB, IHC-P, FC 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRhesus (Macaca mulatta), Chicken (Gallus gallus), Horse (Equus caballus), Human (Homo sapiens), Zebrafish (Danio rerio), Marmoset, O. mykiss (Oncorhynchus mykiss)
CloneMO45363FYA
SpecificityThis antibody binds to Rhesus IL7R.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found. (From NCBI)
Product OverviewMouse Anti-Rhesus IL7R Antibody is a mouse antibody against IL7R. It can be used for IL7R detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesIL7R
UniProt IDF7G3I0
Protein RefseqThe length of the protein is 459 amino acids long.
The sequence is show below: MTILGTTFGMVFSLLQVVSGESGYAQNGDLEDAELDDYSFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLSFRKLQEIYFIETKKFLLIGKSNICVKVGGKSLTCKKIDLTTIVKPEAPFDLSVIYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWMHVNLSSTKLTLLQRNLQPEAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTPEINNSPGEMDPILLTISLLSFFSVALLVILACVLWKKRIKPIVWPSLPDHKKTLEHLCKKPRKNLNVSFNPESFLDCQIHRVDDIQARDEVEGFLQDTFPQQLEESKKQRLGGDVQSPSCPSEDVVITPESFERDSSLRCLAGNVSACDAPILSSSRSLDCRESGKNGPHVYQDLLLSLGTTNSTLPPPFSLPSGILTLNPVAQGQPILTSLGSNQEEAYVTMSSFYQNQ.

Reference

Reference1. Cordes, S., Mortlock, R. D., Truitt, L., Yang, D., Espinoza, D. A., Fan, X., ... & Dunbar, C. E. (2021). Single Cell RNA-Seq Characterization of an Adaptive Population of NK Cells after Primary CMV Infection in Rhesus Macaques. Blood, 138, 193.
2. Schott, G., Galarza-Muñoz, G., Trevino, N., Chen, X., Weirauch, M. T., Gregory, S. G., ... & Garcia-Blanco, M. A. (2021). U2AF2 binds IL7R exon 6 ectopically and represses its inclusion. RNA, 27(5), 571-583.
For Research Use Only | Not For Clinical Use.
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