AibGenesis™ Mouse Anti-PDE6A Antibody (CBMOAB-54130FYA)


Cat: CBMOAB-54130FYA

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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-54130FYA Monoclonal Rhesus (Macaca mulatta), Cattle (Bos taurus), Dog (Canis lupus familiaris), Zebrafish (Danio rerio) WB, ELISA MO54130FYA 100 µg
CBMOAB-92012FYA Monoclonal Zebrafish (Danio rerio) WB, ELISA MO92012FYA 100 µg
MO-AB-17679R Monoclonal Cattle (Bos taurus) WB, ELISA MO17679R 100 µg
MO-AB-32645W Monoclonal Dog (Canis lupus familiaris) WB, ELISA MO32645W 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityRhesus (Macaca mulatta), Cattle (Bos taurus), Dog (Canis lupus familiaris), Zebrafish (Danio rerio)
CloneMO54130FYA
SpecificityThis antibody binds to Rhesus PDE6A.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa. (From NCBI)
Product OverviewMouse Anti-Rhesus PDE6A Antibody is a mouse antibody against PDE6A. It can be used for PDE6A detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesPDE6A
UniProt IDF6SMY5
Protein RefseqThe length of the protein is 860 amino acids long.
The sequence is show below: MGEVTAEEVEKFLDSNIGFAKQYYNLHYRAKVISDLLGAKEAAVDFSNYHSPSSVEESEIIFDLLRDFQENLQTEKCIFNVMKKLCFLLQADRMSLFMYRTRNGIAELATRLFNVHKDAVLEDCLVMPDQEIVFPLDMGVVGHVAHSKKIANVPNTEEDEHFCDFVDILTEYKTKNILASPIMNGKDVVAIIMAVNKVDGSHFTKRDEEILLKYLNFANLIMKVYHLSYLHNCETRRGQILLWSGSKVFEELTDIERQFHKALYTVRAFLNCDRYSVGLLDMTKQKEFFDVWPVLMGEVPPYSGPRTPDGREINFYKVIDYILHGKEDIKVIPNPPPDHWALVSGLPTYVAQNGLICNIMNAPAEDFFAFQKEPLDESGWMIKNVLSMPIVNKKEEIVGVATFYNRKDGKPFDEMDETLMESLAQFLGWSVLNPDTYESMNKLENRKDIFQDIVKYHVKCDNEEIQKILKTREVYGKEPWECEEEELAEILQAELPDAEKYEINKFHFSDLPLTELELVKCGIQMYYELKVVDKFHIPQEALVRFMYSLSKGYRKITYHNWRHGFNVGQTMFSLLVTGKLKRYFTDLEALAMVTAAFCHDIDHRGTNNLYQMKSQNPLAKLHGSSILERHHLEFGKTLLRDESLNIFQNLNRRQHEHAIHMMDIAIIATDLALYFKKRTMFQKIVDQSKTYESEQEWTQYMMLEQTRKEIVMAMMMTACDLSAITKPWEVQSQVALLVAAEFWEQGDLERTVLQQNPIPMMDRNKADELPKLQVGFIDFVCTFVYKEFSRFHKEITPMLDGITNNRKEWKALADEYDAKMKVQEEEKQKQQSAKPAAAGNQLGGNPSPGGATTSKSCCIQ.
For Research Use Only | Not For Clinical Use.
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